Cyclo(Ala-Arg-Gly-Asp-3-Aminomethylbenzoyl)

• Catalog No.: C9357
• CAS Number: 153381-95-4
• M. F.: C23H32N8O7
• M. W.: 532.54958
• Purity: ≥96% (HPLC)

SYNONYMS

• IUPAC name: 2-[(5S,11S,14S)-11-(3-carbamimidamidopropyl)-14-methyl-4,7,10,13,16-pentaoxo-3,6,9,12,15-pentaazabicyclo[15.3.1]henicosa-1(20),17(21),18-trien-5-yl]acetic acid
• IUPAC Traditional name: [(5S,11S,14S)-11-(3-carbamimidamidopropyl)-14-methyl-4,7,10,13,16-pentaoxo-3,6,9,12,15-pentaazabicyclo[15.3.1]henicosa-1(20),17(21),18-trien-5-yl]acetic acid
• Synonyms: XJ735

DATABASE IDS

• MDL Number: MFCD11046000
• CAS Number: 153381-95-4

PROPERTIES

• Empirical Formula (Hill Notation): C23H32N8O7
• Purity: ≥96% (HPLC)
• Gene Information: human ... NPY(4852)
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• Storage Temperature: -20°C
• German water hazard class: 3

DETAILS

Description (English)

Amino Acid Sequence
Ala-Arg-Gly-Asp-3-Aminomethylbenzoyl
Biochem/physiol Actions
Antagonist of RGD peptidomimetic αVβ3 integrin containing both anionic and cationic binding sites that straddle the RGD binding domain.
Cyclo(Ala-Arg-Gly-Asp-3-Aminomethylbenzoyl) (XJ735) is an RGD containing cyclic peptide (peptidomimetic) used as an antagonist specific to integrin αvβ3. XJ735 is used to study the role of integrin αvβ3 in cell-matrix interactions and processes.

Description (简体中文)

Amino Acid Sequence
Ala-Arg-Gly-Asp-3-Aminomethylbenzoyl
Biochem/physiol Actions
Antagonist of RGD peptidomimetic αVβ3 integrin containing both anionic and cationic binding sites that straddle the RGD binding domain.