Indomethacin heptyl ester

• Catalog No.: I7904
• M. F.: C26H30ClNO4
• M. W.: 455.9737
• Purity: ≥98% (HPLC)

SYNONYMS

• IUPAC name: heptyl 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetate
• IUPAC Traditional name: heptyl 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetate

DATABASE IDS

• MDL Number: MFCD03412025

PROPERTIES

• Empirical Formula (Hill Notation): C26H30ClNO4
• Potency: 0.04 μM IC50 (for human recombinat COX-2)
• Purity: ≥98% (HPLC)
• Shipped in: wet ice
• Apperance: methyl acetate solution
• Flash Point: -16 °C
• Flash Point: 3 °F
• European Hazard Symbols: Flammable (F)
• European Hazard Symbols: Irritant (Xi)
• RID/ADR: UN 1231 3/PG 2
• Risk Statements: 11-36-66-67
• RTECS: AI9100000
• Safety Statements: 16-26-29-33-36
• Storage Temperature: -20°C
• Hazard Class: 3
• UN Number: 1231
• Packing Group: 2
• German water hazard class: 1

DETAILS

Description (English)

Application
Used to inhibit COX-1 and COX-2. To achieve 50% inhibition of human recombinant COX-2 use I7904 at 0.04 uM/mL .
Biochem/physiol Actions
Potent cyclooxygenase-2 inhibitor. 1700 times greater activity against COX-2 than COX-1.
Other Notes
Derivatized indomethacin.

Description (简体中文)

Application
Used to inhibit COX-1 and COX-2. To achieve 50% inhibition of human recombinant COX-2 use I7904 at 0.04 uM/mL .
Biochem/physiol Actions
Potent cyclooxygenase-2 inhibitor. 1700 times greater activity against COX-2 than COX-1.
Other Notes
Derivatized indomethacin.