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Ticarcillin disodium salt

Catalog No. T5639 Name Sigma Aldrich
CAS Number 4697-14-7 Website http://www.sigmaaldrich.com
M. F. C15H14N2Na2O6S2 Telephone 1-800-521-8956
M. W. 428.391 Fax
Purity ≥95% Email
Storage Chembase ID: 155569

SYNONYMS

Title
替卡西林 二钠盐
IUPAC name
disodium (2S,5R,6R)-6-[(2R)-2-carboxylato-2-(thiophen-3-yl)acetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
IUPAC Traditional name
disodium ticarcillin(2-)
Synonyms
(2S,5R,6R)-6-[[(2R)-Carboxy-3-thienylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid disodium salt

DATABASE IDS

MDL Number MFCD07787410
CAS Number 4697-14-7
PubChem SID 24900306

PROPERTIES

Empirical Formula (Hill Notation) C15H14N2Na2O6S2
Purity ≥95%
GHS Pictograms GHS07
GHS Pictograms GHS08
GHS Signal Word Danger
GHS Hazard statements H315-H319-H334-H335
European Hazard Symbols Harmful Harmful (Xn)
MSDS Link Download
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Faceshields, Gloves
GHS Precautionary statements P261-P305 + P351 + P338-P342 + P311
Risk Statements 36/37/38-42-43
RTECS XM9410000
Safety Statements 26-36/37
Storage Temperature 2-8°C
German water hazard class 2

DETAILS

Description (English)
Other Notes
β-Lactam antibiotic
Application
Ticarcillin is a semisynthetic antibiotic with a broad spectrum of bactericidal activity against many gram-positive and gram-negative aerobic and anaerobic bacteria. It is commonly used in combination with clavulanate in order to improve it′s efficacy1. It is used to study appropriate dosing in pediatric patients who have cystic fibrosis2.
Biochem/physiol Actions
Ticarcillin is a β-Lactam antibiotic that prevents bacterial cell wall biosynthesis at the level of peptidogylcan cross-linking by inhibiting peptidoglycan transpeptidases. It is derived from penicillin and is similar to carbenicillin in action. Ticarcillin is susceptible to degradation by β-lactamases1.
Description (简体中文)
Other Notes
β-Lactam antibiotic
Application
Ticarcillin is a semisynthetic antibiotic with a broad spectrum of bactericidal activity against many gram-positive and gram-negative aerobic and anaerobic bacteria. It is commonly used in combination with clavulanate in order to improve it′s efficacy1. It is used to study appropriate dosing in pediatric patients who have cystic fibrosis2.
Biochem/physiol Actions
Ticarcillin is a β-Lactam antibiotic that prevents bacterial cell wall biosynthesis at the level of peptidogylcan cross-linking by inhibiting peptidoglycan transpeptidases. It is derived from penicillin and is similar to carbenicillin in action. Ticarcillin is susceptible to degradation by β-lactamases1.

REFERENCES