5,6-Dehydroarachidonic acid

• Catalog No.: D2154
• CAS Number: 58688-54-3
• M. F.: C20H30O2
• M. W.: 302.451
• Purity: ≥98%

SYNONYMS

• IUPAC name: icosa-8,11,14-trien-5-ynoic acid
• IUPAC Traditional name: icosa-8,11,14-trien-5-ynoic acid
• Synonyms: cis-8,11,14-Eicosatrien-5-ynoic acid; 5,6-dehydro AA

DATABASE IDS

• CAS Number: 58688-54-3
• PubChem SID: 24893642
• MDL Number: MFCD00065715

PROPERTIES

• Empirical Formula (Hill Notation): C20H30O2
• Purity: ≥98%
• Shipped in: wet ice
• Apperance: ethanol solution
• Flash Point: 17 °C
• Flash Point: 62 °F
• European Hazard Symbols: Flammable (F)
• RID/ADR: UN 1170 3/PG 2
• Risk Statements: 11-16
• Safety Statements: 16
• Storage Temperature: -20°C
• Hazard Class: 3
• UN Number: 1170
• Packing Group: 2
• German water hazard class: 1

DETAILS

Description (English)

Biochem/physiol Actions
Inhibits 5-lipoxygenase of guinea pig leukocytes with an IC50 of 10 μM. In extracts of rat basophilic leukemia cells preincubated with 5,6-dehydro AA, the Ki for the conversion of arachidonic acid to 5-HPETE is 15 μM.
General description
An analog of arachidonic acid in which the 5,6 double bond has been replaced with an acetylene group.

Description (简体中文)

Biochem/physiol Actions
Inhibits 5-lipoxygenase of guinea pig leukocytes with an IC50 of 10 μM. In extracts of rat basophilic leukemia cells preincubated with 5,6-dehydro AA, the Ki for the conversion of arachidonic acid to 5-HPETE is 15 μM.
General description
An analog of arachidonic acid in which the 5,6 double bond has been replaced with an acetylene group.