Calphostin C from Cladosporium cladosporioides

• Catalog No.: C6303
• CAS Number: 121263-19-2
• M. F.: C44H38O14
• M. W.: 790.76412
• Purity: ≥90% (HPLC)

SYNONYMS

• IUPAC name: 1-(4,9-dihydroxy-12-{2-[(4-hydroxyphenoxycarbonyl)oxy]propyl}-2,6,7,11-tetramethoxy-3,10-dioxo-3,10-dihydroperylen-1-yl)propan-2-yl benzoate
• IUPAC Traditional name: 1-(4,9-dihydroxy-12-{2-[(4-hydroxyphenoxycarbonyl)oxy]propyl}-2,6,7,11-tetramethoxy-3,10-dioxoperylen-1-yl)propan-2-yl benzoate
• Synonyms: UCN-1028C

DATABASE IDS

• PubChem SID: 24892857
• CAS Number: 121263-19-2
• MDL Number: MFCD00133155

PROPERTIES

• Empirical Formula (Hill Notation): C44H38O14
• Purity: ≥90% (HPLC)
• Apperance: red to brown powder
• Solubility: DMF: soluble1 mg/mL
• Solubility: DMSO: soluble1 mg/mL
• Solubility: ethanol: soluble1 mg/mL
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• Storage Temperature: -20°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Highly specific inhibitor of protein kinase C (IC50 = 50 nM); requires light for activation. At higher concentrations (100 nM or greater), it has been shown to inhibit cell proliferation and induce apoptosis in vitro.

Description (简体中文)

Biochem/physiol Actions
Highly specific inhibitor of protein kinase C (IC50 = 50 nM); requires light for activation. At higher concentrations (100 nM or greater), it has been shown to inhibit cell proliferation and induce apoptosis in vitro.