Z-Pro-Leu-Gly hydroxamate

• Catalog No.: C8537
• CAS Number: 103145-74-0
• M. F.: C21H30N4O6
• M. W.: 434.4861
• Purity: ≥97% (TLC)

SYNONYMS

• IUPAC name: benzyl 2-[(1-{[(hydroxycarbamoyl)methyl]carbamoyl}-3-methylbutyl)carbamoyl]pyrrolidine-1-carboxylate
• IUPAC Traditional name: benzyl 2-({1-[(hydroxycarbamoyl)methylcarbamoyl]-3-methylbutyl}carbamoyl)pyrrolidine-1-carboxylate

DATABASE IDS

• MDL Number: MFCD00083286
• PubChem SID: 24893070
• CAS Number: 103145-74-0

PROPERTIES

• Empirical Formula (Hill Notation): C21H30N4O6
• Purity: ≥97% (TLC)
• Gene Information: human ... MMP1 (includes EG:4312)(4312)mouse ... MMP1 (includes EG:4312)(83995)rat ... MMP1 (includes EG:4312)(300339)
• Solubility: acetic acid: water (1:1): soluble50 mg/mL
• Solubility: methanol: soluble50 mg/mL
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• Storage Temperature: -20°C
• German water hazard class: 3

DETAILS

Description (English)

Amino Acid Sequence
Z-Pro-Leu-Gly
Biochem/physiol Actions
A hydroxamate inhibitor of human collagenases (MMP-1; matrix metalloproteinase 1). It is a substrate analog that interacts with the zinc moiety of MMP-1.

Description (简体中文)

Amino Acid Sequence
Z-Pro-Leu-Gly
Biochem/physiol Actions
A hydroxamate inhibitor of human collagenases (MMP-1; matrix metalloproteinase 1). It is a substrate analog that interacts with the zinc moiety of MMP-1.