Lycorine hydrochloride

• Catalog No.: L5139
• CAS Number: 2188-68-3
• M. F.: C16H18ClNO4
• M. W.: 323.77142
• Purity: ≥98% (TLC)

SYNONYMS

• IUPAC name: (1S,17S,18S,19S)-5,7-dioxa-12-azapentacyclo[10.6.1.0^2,^1^0.0^4,^8.0^1^5,^1^9]nonadeca-2,4(8),9,15-tetraene-17,18-diol hydrochloride
• IUPAC Traditional name: lycorine hydrochloride

DATABASE IDS

• PubChem SID: 24896395
• CAS Number: 2188-68-3
• MDL Number: MFCD00243111

PROPERTIES

• Empirical Formula (Hill Notation): C16H17NO4 · HCl
• Purity: ≥98% (TLC)
• Apperance: powder
• GHS Signal Word: Danger
• GHS Hazard statements: H301
• European Hazard Symbols: Toxic (T)
• Personal Protective Equipment: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
• GHS Precautionary statements: P301 + P310
• RID/ADR: UN 2811 6.1/PG 3
• Risk Statements: 25
• Safety Statements: 45
• Storage Temperature: 2-8°C
• Hazard Class: 6.1
• UN Number: 2811
• Packing Group: 3
• German water hazard class: 3

DETAILS

Description (English)

Caution
Protect from light.
Biochem/physiol Actions
A selective inhibitor of peptidyl transferase center (PTC). In HL-60 (leukemia) cells, lycorine arrests the cell cycle at G2/M and induces apoptosis by a caspase-mediated pathway.1

Description (简体中文)

Caution
Protect from light.
Biochem/physiol Actions
A selective inhibitor of peptidyl transferase center (PTC). In HL-60 (leukemia) cells, lycorine arrests the cell cycle at G2/M and induces apoptosis by a caspase-mediated pathway.1