Sodium cholate hydrate

• Catalog No.: C9282
• CAS Number: 206986-87-0
• M. F.: C24H41NaO6
• M. W.: 448.56851

SYNONYMS

• Title: Sodium cholate 水合物
• IUPAC name: sodium (4R)-4-[(1S,2S,5R,7S,9R,10R,11S,14R,15R,16S)-5,9,16-trihydroxy-2,15-dimethyltetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadecan-14-yl]pentanoate hydrate
• IUPAC Traditional name: sodium cholate hydrate
• Synonyms: 3α,7α,12α-Trihydroxy-5β-cholan-24-oic acid sodium salt; 3α,7α,12α-Trihydroxy-5β-cholan-24-oic acid 钠盐; Cholalic acid 钠盐; Cholalic acid sodium salt

DATABASE IDS

• EC Number: 206-643-5
• PubChem SID: 24893147
• MDL Number: MFCD00150749
• Beilstein Number: 3582354
• CAS Number: 206986-87-0

PROPERTIES

• Description: anionic
• Empirical Formula (Hill Notation): C24H39NaO5 · xH2O
• Mol. Weight: micellar avg mol wt 900-1300
• Product Line: BioReagent
• Suitability: suitable for cell culture
• Aggregation Number of Micelle: 2-3
• Aggregation Number of Micelle: 2-3
• Critical Micelle Concentration: 9-15 mM(20-25°C)
• Hydrophilic Lipophilic Balance: 18
• Hydrophilic Lipophilic Balance: 18
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• German water hazard class: 3

DETAILS

Description (English)

Application
Non-denaturing detergent used for extraction of membrane proteins.
Cholate is a bile acid produced in liver during cholesterol breakdown. Cholate downregulates cholesterol-7-α-hydroxylase (rate-limiting step in bile acid synthesis). Cholate, an anionic detergent, is used alone and in combination with urea to extract and reconstitute membrane proteins and protein complexes.

Description (简体中文)

Application
Non-denaturing detergent used for extraction of membrane proteins.
Cholate is a bile acid produced in liver during cholesterol breakdown. Cholate downregulates cholesterol-7-α-hydroxylase (rate-limiting step in bile acid synthesis). Cholate, an anionic detergent, is used alone and in combination with urea to extract and reconstitute membrane proteins and protein complexes.