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Fostriecin sodium salt from Streptomyces pulveraceus_Molecular_structure_CAS_87860-39-7)
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Fostriecin sodium salt from Streptomyces pulveraceus

Catalog No. F4425 Name Sigma Aldrich
CAS Number 87860-39-7 Website http://www.sigmaaldrich.com
M. F. C19H26NaO9P Telephone 1-800-521-8956
M. W. 452.367871 Fax
Purity ≥98% (HPLC) Email
Storage Chembase ID: 155484

SYNONYMS

IUPAC name
sodium (6R)-6-[(3R,4R,6R)-4-(hydrogen phosphonatooxy)-3,6,13-trihydroxy-3-methyltrideca-1,7,9,11-tetraen-1-yl]-5,6-dihydro-2H-pyran-2-one
IUPAC Traditional name
sodium (6R)-6-[(3R,4R,6R)-4-(hydrogen phosphonatooxy)-3,6,13-trihydroxy-3-methyltrideca-1,7,9,11-tetraen-1-yl]-5,6-dihydropyran-2-one

DATABASE IDS

PubChem SID 24894863
CAS Number 87860-39-7
MDL Number MFCD09971059

PROPERTIES

Empirical Formula (Hill Notation) C19H26NaO9P
Purity ≥98% (HPLC)
MSDS Link Download
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
RTECS UQ0600000
Storage Temperature -20°C
German water hazard class 3

DETAILS

Description (English)
Packaging
Packaged under argon.
Biochem/physiol Actions
Fostriecin was discovered as an anti-tumor antibiotic isolated from the fermentation beer of Streptomyces pulveraceus (subspecies fostreus). Fostriecin has antitumor activity against a wide spectrum of tumor cells in vitro and excellent activity against P388 and L1210 leukemias in vivo. The antitumor activity of fostriecin originates from its ability to interfere with the reversible phosphorylation of proteins that are critical for progression through the cell cycle.
Description (简体中文)
包装
Packaged under argon.
Biochem/physiol Actions
Fostriecin was discovered as an anti-tumor antibiotic isolated from the fermentation beer of Streptomyces pulveraceus (subspecies fostreus). Fostriecin has antitumor activity against a wide spectrum of tumor cells in vitro and excellent activity against P388 and L1210 leukemias in vivo. The antitumor activity of fostriecin originates from its ability to interfere with the reversible phosphorylation of proteins that are critical for progression through the cell cycle.

REFERENCES