Fostriecin sodium salt from Streptomyces pulveraceus

• Catalog No.: F4425
• CAS Number: 87860-39-7
• M. F.: C19H26NaO9P
• M. W.: 452.367871
• Purity: ≥98% (HPLC)

SYNONYMS

• IUPAC name: sodium (6R)-6-[(3R,4R,6R)-4-(hydrogen phosphonatooxy)-3,6,13-trihydroxy-3-methyltrideca-1,7,9,11-tetraen-1-yl]-5,6-dihydro-2H-pyran-2-one
• IUPAC Traditional name: sodium (6R)-6-[(3R,4R,6R)-4-(hydrogen phosphonatooxy)-3,6,13-trihydroxy-3-methyltrideca-1,7,9,11-tetraen-1-yl]-5,6-dihydropyran-2-one

DATABASE IDS

• PubChem SID: 24894863
• CAS Number: 87860-39-7
• MDL Number: MFCD09971059

PROPERTIES

• Empirical Formula (Hill Notation): C19H26NaO9P
• Purity: ≥98% (HPLC)
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• RTECS: UQ0600000
• Storage Temperature: -20°C
• German water hazard class: 3

DETAILS

Description (English)

Packaging
Packaged under argon.
Biochem/physiol Actions
Fostriecin was discovered as an anti-tumor antibiotic isolated from the fermentation beer of Streptomyces pulveraceus (subspecies fostreus). Fostriecin has antitumor activity against a wide spectrum of tumor cells in vitro and excellent activity against P388 and L1210 leukemias in vivo. The antitumor activity of fostriecin originates from its ability to interfere with the reversible phosphorylation of proteins that are critical for progression through the cell cycle.

Description (简体中文)

包装
Packaged under argon.
Biochem/physiol Actions
Fostriecin was discovered as an anti-tumor antibiotic isolated from the fermentation beer of Streptomyces pulveraceus (subspecies fostreus). Fostriecin has antitumor activity against a wide spectrum of tumor cells in vitro and excellent activity against P388 and L1210 leukemias in vivo. The antitumor activity of fostriecin originates from its ability to interfere with the reversible phosphorylation of proteins that are critical for progression through the cell cycle.