9-cis-Retinoic acid

• Catalog No.: R4643
• CAS Number: 5300-03-8
• M. F.: C20H28O2
• M. W.: 300.43512
• Purity: ≥98% (HPLC)

SYNONYMS

• Title: 9-顺式视黄酸
• IUPAC name: (2E,4E,6Z,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid
• IUPAC Traditional name: alitretinoin
• Synonyms: alitretinoin; 9-cis-Tretinoin; 9-顺式维甲酸

DATABASE IDS

• CAS Number: 5300-03-8
• PubChem SID: 24899373
• MDL Number: MFCD00270072

PROPERTIES

• Empirical Formula (Hill Notation): C20H28O2
• Purity: ≥98% (HPLC)
• Gene Information: human ... RARA(5914), RARB(5915), RARG(5916), RXRA(6256), RXRB(6257), RXRG(6258)
• GHS Signal Word: Danger
• GHS Hazard statements: H315-H319-H335-H360
• European Hazard Symbols: Toxic (T)
• Personal Protective Equipment: Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
• GHS Precautionary statements: P201-P261-P305 + P351 + P338-P308 + P313
• Risk Statements: 61-36/37/38
• Safety Statements: 53-26-36/37/39-45
• Storage Temperature: -20°C
• German water hazard class: 3

DETAILS

Description (English)

Packaging
Sealed ampule
Biochem/physiol Actions
Ligand for both the retinoic acid receptor (RAR) and the retinoid X receptor (RXR) that act as transcription factors to regulate the growth and differentiation of normal and malignant cells.
Other Notes
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. R4643.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

Description (简体中文)

包装
密封安瓿瓶
Biochem/physiol Actions
视黄酸受体 (RAR) 和类视色素 X 受体 (RXR) 的配体，这两种受体作为转录因子调控正常和恶性细胞的生长和分化。
Other Notes
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. R4643.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.