Cefamandole nafate

• Catalog No.: C7270
• CAS Number: 42540-40-9
• M. F.: C19H17N6NaO6S2
• M. W.: 512.49465
• Purity: ~95%

SYNONYMS

• IUPAC name: sodium (6R,7R)-7-[(2R)-2-(formyloxy)-2-phenylacetamido]-3-{[(1-methyl-1H-1,2,3,4-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
• IUPAC Traditional name: sodium (6R,7R)-7-[(2R)-2-(formyloxy)-2-phenylacetamido]-3-{[(1-methyl-1,2,3,4-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
• Synonyms: Cefamandole formate sodium salt

DATABASE IDS

• EC Number: 255-877-4
• PubChem SID: 24892951
• MDL Number: MFCD00864877
• CAS Number: 42540-40-9

PROPERTIES

• Linear Formula: C19H17N6O6S2Na
• Purity: ~95%
• GHS Signal Word: Danger
• GHS Hazard statements: H315-H317-H319-H334-H335
• European Hazard Symbols: Harmful (Xn)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Faceshields, Gloves
• GHS Precautionary statements: P261-P280-P305 + P351 + P338-P342 + P311
• Risk Statements: 36/37/38-42/43
• RTECS: XI0380000
• Safety Statements: 26-36
• German water hazard class: 3

DETAILS

Description (English)

Physical form
sodium carbonate: approx. 5%
Application
Cefamandole is used to study the effects of expression and inhibition of PBP 2A and other penicillin-binding proteins (PDPs) on bacterial cell wall mucopeptide synthesis.
Biochem/physiol Actions
Cefamandole nafate inhibits bacterial cell wall synthesis by inhibiting PBP 2A and other penicillin-binding proteins. Cefamandole nafate has been shown to be rapidly converted to cefamandolein bacteriological media 1.

Description (简体中文)

Physical form
sodium carbonate: approx. 5%
Application
Cefamandole is used to study the effects of expression and inhibition of PBP 2A and other penicillin-binding proteins (PDPs) on bacterial cell wall mucopeptide synthesis.
Biochem/physiol Actions
Cefamandole nafate inhibits bacterial cell wall synthesis by inhibiting PBP 2A and other penicillin-binding proteins. Cefamandole nafate has been shown to be rapidly converted to cefamandolein bacteriological media 1.