(-)-N6-(2-Phenylisopropyl)adenosine

• Catalog No.: P4532
• CAS Number: 38594-96-6
• M. F.: C19H23N5O4
• M. W.: 385.41702

SYNONYMS

• IUPAC name: (2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-{[(2R)-1-phenylpropan-2-yl]amino}-9H-purin-9-yl)oxolane-3,4-diol
• IUPAC Traditional name: (2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-{[(2R)-1-phenylpropan-2-yl]amino}purin-9-yl)oxolane-3,4-diol
• Synonyms: N6-(L-2-Phenylisopropyl)adenosine; (R)-N6-(1-Methyl-2-phenylethyl)adenosine; R-(-)-PIA

DATABASE IDS

• PubChem SID: 24277681
• EC Number: 254-028-5
• CAS Number: 38594-96-6
• MDL Number: MFCD00069194

PROPERTIES

• Empirical Formula (Hill Notation): C19H23N5O4
• Potency: 1.17 nM Ki for A1 receptors (using [3H]CHA in rat forebrain preparations)
• Gene Information: human ... ADORA1(134)
• Apperance: white solid
• Solubility: H2O: slightly soluble0.3 mg/mL (Solutions may be stored for several days at 4°C.)
• Solubility: 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: soluble1.6 mg/mL (Solutions may be stored for several days at 4°C.)
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
A1 adenosine receptor agonist. Affinity for adenosine receptor is approx. 100× that of the (+)-isomer.

Description (简体中文)

Biochem/physiol Actions
A1 adenosine receptor agonist. Affinity for adenosine receptor is approx. 100× that of the (+)-isomer.