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Sulfacetamide sodium salt

Catalog No. S8647 Name Sigma Aldrich
CAS Number 6209-17-2 Website http://www.sigmaaldrich.com
M. F. C8H12N2NaO4S Telephone 1-800-521-8956
M. W. 255.24665 Fax
Purity Email
Storage Chembase ID: 155424

SYNONYMS

IUPAC name
N-(4-aminobenzenesulfonyl)acetamide hydrate sodium
IUPAC Traditional name
sulfacetamide hydrate sodium
Synonyms
N-(p-Aminobenzenesulfonyl)acetamide

DATABASE IDS

CAS Number 6209-17-2
MDL Number MFCD00007885
PubChem SID 24899806

PROPERTIES

Linear Formula C8H9N2O3SNa
MSDS Link Download
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
German water hazard class 3

DETAILS

Description (English)
Application
Sulfacetamide is an antibiotic that is used to treat skin infections and urinary tract infections1. Sulfacetamide is used to study the treatment of acne and seborrheic dermatitis. It is used to study neonatal chlamydial conjunctivitis and meningococcal conjunctivitis.
Biochem/physiol Actions
Sulfacetamide is a sulfonamide antibiotic that blocks the synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase. Sulfacetamide is a competitive inhibitor of bacterial para-aminobenzoic acid (PABA), which is required for bacterial synthesis of folic acid1. It is active against Gram positive bacteria, Gram negative bacteria and Chlamydia. Mode of resistance is via the alteration of dihydropteroate synthase or alternative pathway for folic acid synthesis.
Description (简体中文)
Application
Sulfacetamide is an antibiotic that is used to treat skin infections and urinary tract infections1. Sulfacetamide is used to study the treatment of acne and seborrheic dermatitis. It is used to study neonatal chlamydial conjunctivitis and meningococcal conjunctivitis.
Biochem/physiol Actions
Sulfacetamide is a sulfonamide antibiotic that blocks the synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase. Sulfacetamide is a competitive inhibitor of bacterial para-aminobenzoic acid (PABA), which is required for bacterial synthesis of folic acid1. It is active against Gram positive bacteria, Gram negative bacteria and Chlamydia. Mode of resistance is via the alteration of dihydropteroate synthase or alternative pathway for folic acid synthesis.

REFERENCES