Glybenclamide

• Catalog No.: G0639
• CAS Number: 10238-21-8
• M. F.: C23H28ClN3O5S
• M. W.: 494.00352
• Purity: ≥99% (HPLC)

SYNONYMS

• Title: 格列本脲
• IUPAC name: 5-chloro-N-[2-(4-{[(cyclohexylcarbamoyl)amino]sulfonyl}phenyl)ethyl]-2-methoxybenzamide
• IUPAC Traditional name: glyburide
• Synonyms: 5-氯-N-[4-(环己基脲磺酰)苯乙基]-2-甲氧基苯甲酰胺; 5-Chloro-N-[4-(cyclohexylureidosulfonyl)phenethyl]-2-methoxybenzamide; Glyburide; 格列本脲; N-p-[2-(5-Chloro-2-methoxybenzamido)ethyl]benzenesulfonyl-N′-cyclohexylurea; N-对[2-(5-氯-2-甲氧基苯甲酰氨基)乙基]苯磺酰基-N′-环己基脲

DATABASE IDS

• PubChem SID: 24277838
• EC Number: 233-570-6
• CAS Number: 10238-21-8
• MDL Number: MFCD00056625

PROPERTIES

• Solubility: ethanol: soluble2 mg/mL
• Solubility: DMSO: soluble
• Solubility: H2O: insoluble
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• RTECS: YS4725200
• Storage Temperature: 2-8°C
• German water hazard class: 2
• Empirical Formula (Hill Notation): C23H28ClN3O5S
• Purity: ≥99% (HPLC)
• Gene Information: human ... KCNH2(3757), KCNJ1(3758), KCNJ11(3767)rat ... Kcnj1(24521)

DETAILS

Description (English)

Biochem/physiol Actions
Selectively blocks ATP-sensitive K+ channels; high affinity binding sites found in brain, pancreatic β cells, and cardiovascular system.

Description (简体中文)

Biochem/physiol Actions
Selectively blocks ATP-sensitive K+ channels; high affinity binding sites found in brain, pancreatic β cells, and cardiovascular system.