Sisomicin sulfate salt

• Catalog No.: S7796
• CAS Number: 53179-09-2
• M. F.: C38H84N10O34S5
• M. W.: 1385.44516
• Purity: ≥80% (TLC)

SYNONYMS

• IUPAC name: bis((2R,3R,4R,5R)-2-{[(1S,2S,3R,4S,6R)-4,6-diamino-3-{[(2S,3R)-3-amino-6-(aminomethyl)-3,4-dihydro-2H-pyran-2-yl]oxy}-2-hydroxycyclohexyl]oxy}-5-methyl-4-(methylamino)oxane-3,5-diol); pentakis(sulfuric acid)
• IUPAC Traditional name: bis(SISO); pentakis(sulfuric acid)

DATABASE IDS

• EC Number: 258-414-4
• CAS Number: 53179-09-2

PROPERTIES

• Linear Formula: 2C19H37N5O7 · 5H2SO4
• Purity: ≥80% (TLC)
• GHS Signal Word: Danger
• GHS Hazard statements: H312-H332-H360
• European Hazard Symbols: Toxic (T)
• Personal Protective Equipment: Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
• GHS Precautionary statements: P201-P280-P308 + P313
• Risk Statements: 61-20/21/22
• RTECS: WK2288000
• Safety Statements: 53-22-36/37/39-45
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (English)

Application
Sisomicin is an aminoglycoside antibiotic isolated from Micromonopora inyoensis. It is effective against most strains of Klebsiellk spp., Escherichia coli, P. aeruginosa, Enterobacter and Proteus spp.. It is a potential treatment for conjunctiva 1. It is used in disk and tube dilution sensitivity test2.
Biochem/physiol Actions
Sisomicin interferes with protein synthesis at the level of functional ribosome assembly. The mechanism is similar to that of gentamycin. Sisomicin closely resembles gentamicin but is more effective against Pseudomonas aeruginosa and indole-positive Proteus3.

Description (简体中文)

Application
Sisomicin is an aminoglycoside antibiotic isolated from Micromonopora inyoensis. It is effective against most strains of Klebsiellk spp., Escherichia coli, P. aeruginosa, Enterobacter and Proteus spp.. It is a potential treatment for conjunctiva 1. It is used in disk and tube dilution sensitivity test2.
Biochem/physiol Actions
Sisomicin interferes with protein synthesis at the level of functional ribosome assembly. The mechanism is similar to that of gentamycin. Sisomicin closely resembles gentamicin but is more effective against Pseudomonas aeruginosa and indole-positive Proteus3.