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Puromycin dihydrochloride from Streptomyces alboniger_Molecular_structure_CAS_58-58-2)
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Puromycin dihydrochloride from Streptomyces alboniger

Catalog No. P8833 Name Sigma Aldrich
CAS Number 58-58-2 Website http://www.sigmaaldrich.com
M. F. C22H31Cl2N7O5 Telephone 1-800-521-8956
M. W. 544.43144 Fax
Purity ≥98% (HPLC) Email
Storage Chembase ID: 154171

SYNONYMS

Title
Puromycin dihydrochloride 二盐酸盐 来源于白色链球菌
IUPAC name
(2S)-2-amino-N-[(2S,3S,4R,5R)-5-[6-(dimethylamino)-9H-purin-9-yl]-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]-3-(4-methoxyphenyl)propanamide dihydrochloride
IUPAC Traditional name
puromycin dihydrochloride
Synonyms
3′-[α-Amino-p-methoxyhydrocinnamamido]-3′-deoxy-N,N-dimethyladenosine 二盐酸盐
3′-[α-Amino-p-methoxyhydrocinnamamido]-3′-deoxy-N,N-dimethyladenosine dihydrochloride

DATABASE IDS

EC Number 200-387-8
MDL Number MFCD00012691
PubChem SID 24898984
Beilstein Number 3853613
CAS Number 58-58-2

PROPERTIES

Risk Statements 22
RTECS AU7355000
Storage Temperature -20°C
German water hazard class 3
GHS Pictograms GHS07
GHS Signal Word Warning
GHS Hazard statements H302
European Hazard Symbols Harmful Harmful (Xn)
MSDS Link Download
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Empirical Formula (Hill Notation) C22H29N7O5 · 2HCl
Product Line BioReagent
Purity ≥98% (HPLC)
Quality Level PREMIUM
Suitability suitable for cell culture
Apperance powder
Solubility H2O: soluble50 mg/mL

DETAILS

Description (English)
Frequently Asked Questions
Live Chat and Frequently Asked Questions are available for this Product.
Application
May be used in vitro as a selection agent for cells transfected with puromycin N-acetyl transferase gene (pac).
Biochem/physiol Actions
Nucleoside antibiotic. Protein synthesis inhibitor that causes premature chain termination by acting as an analog of the 3′-terminal end of aminoacyl-tRNA. Prevents growth of bacteria, protozoa, algae, and mammalian cells. Acts very quickly and can kill 99% of cells within 2 days, the resistance gene (puromycin acetyltransferase) gives very effective protection.
Protocols & Applications
Antibiotic Selector for application, solubility, solution stability, working concentration, and mode of action information
Description (简体中文)
Frequently Asked Questions
Live Chat and Frequently Asked Questions are available for this Product.
Application
May be used in vitro as a selection agent for cells transfected with puromycin N-acetyl transferase gene (pac).
Biochem/physiol Actions
Nucleoside antibiotic. Protein synthesis inhibitor that causes premature chain termination by acting as an analog of the 3′-terminal end of aminoacyl-tRNA. Prevents growth of bacteria, protozoa, algae, and mammalian cells. Acts very quickly and can kill 99% of cells within 2 days, the resistance gene (puromycin acetyltransferase) gives very effective protection.
Protocols & Applications
Antibiotic Selector for application, solubility, solution stability, working concentration, and mode of action information

REFERENCES