Aloin

• Catalog No.: B6906
• CAS Number: 1415-73-2
• M. F.: C21H22O9
• M. W.: 418.39398
• Purity: ≥97%

SYNONYMS

• IUPAC name: (10S)-1,8-dihydroxy-3-(hydroxymethyl)-10-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]-9,10-dihydroanthracen-9-one
• IUPAC Traditional name: (10S)-1,8-dihydroxy-3-(hydroxymethyl)-10-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]-10H-anthracen-9-one
• Synonyms: Barbaloin; 1,8-Dihydroxy-10-(β-D-glucopyranosyl)-3-(hydroxymethyl)-9(10H)-anthracenone; Aloin A; 10-β-D-Glucopyranosyl-1,8-dihydroxy-3-(hydroxymethyl)-9(10H)-anthracenone

DATABASE IDS

• Beilstein Number: 6077558
• MDL Number: MFCD00151160
• CAS Number: 1415-73-2
• EC Number: 215-808-0
• PubChem SID: 24891938

PROPERTIES

• Biological Source: from Aloe barbadensis Miller leaves
• Empirical Formula (Hill Notation): C21H22O9
• Purity: ≥97%
• GHS Signal Word: Warning
• GHS Hazard statements: H315-H319-H335
• European Hazard Symbols: Irritant (Xi)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• GHS Precautionary statements: P261-P305 + P351 + P338
• Risk Statements: 36/37/38
• RTECS: LZ6520000
• Safety Statements: 26-36
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (English)

Application
Aloin, a natural mixed diastereomer (A/B) anthracycline from aloe plant, is studied as an antineoplastic agent that enhances melanogenesis and transglutaminase activity. Aloin A is used as a stabilizer in the preparation of gold and silver nanoparticles.
Biochem/physiol Actions
Purgative activity in rats requires activation by Eubacterium sp. strain BAR or similar intestinal anaerobe, presumably by conversion to aloe-emodin anthrone.1

Description (简体中文)

Application
Aloin, a natural mixed diastereomer (A/B) anthracycline from aloe plant, is studied as an antineoplastic agent that enhances melanogenesis and transglutaminase activity. Aloin A is used as a stabilizer in the preparation of gold and silver nanoparticles.
Biochem/physiol Actions
Purgative activity in rats requires activation by Eubacterium sp. strain BAR or similar intestinal anaerobe, presumably by conversion to aloe-emodin anthrone.1