L-Canavanine

• Catalog No.: C1625
• CAS Number: 543-38-4
• M. F.: C5H12N4O3
• M. W.: 176.17378
• Purity: ≥98% (TLC)

SYNONYMS

• Title: L-刀豆氨酸
• IUPAC name: (2S)-2-amino-4-(carbamimidamidooxy)butanoic acid
• IUPAC Traditional name: canavanine
• Synonyms: L-α-Amino-γ-(guanidinooxy)-n-butyric acid

DATABASE IDS

• MDL Number: MFCD00055781
• PubChem SID: 24892427
• CAS Number: 543-38-4

PROPERTIES

• Biological Source: from Canavalia ensiformis
• Empirical Formula (Hill Notation): C5H12N4O3
• Purity: ≥98% (TLC)
• Apperance: powder
• Solubility: H2O: <100 mg/mL
• GHS Signal Word: Warning
• GHS Hazard statements: H302-H312-H332
• European Hazard Symbols: Harmful (Xn)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• GHS Precautionary statements: P280
• Risk Statements: 20/21/22
• RTECS: ES7002000
• Safety Statements: 36
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
A naturally occurring L-amino acid that interferes with L-arginine-utilizing enzymes due to its structural similarity. It is a selective inhibitor of inducible nitric oxide synthase (iNOS). Overproduction of NO by iNOS plays a crucial role in the pathophysiology of septic shock and chronic inflammation.
Canavanine is a naturally occurring L-amino acid that interferes with L-arginine-utilizing enzymes due to its structural similarity. It is a selective inhibitor of inducible nitric oxide synthase (iNOS). Overproduction of NO by iNOS plays a crucial role in the pathophysiology of septic shock and chronic inflammation.
Other Notes
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. C1625.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

Description (简体中文)

Biochem/physiol Actions
A naturally occurring L-amino acid that interferes with L-arginine-utilizing enzymes due to its structural similarity. It is a selective inhibitor of inducible nitric oxide synthase (iNOS). Overproduction of NO by iNOS plays a crucial role in the pathophysiology of septic shock and chronic inflammation.
Other Notes
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. C1625.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.