β-Nicotinamide adenine dinucleotide phosphate, reduced tetra(cyclohexylammonium) salt

• Catalog No.: N5130
• CAS Number: 100929-71-3
• M. F.: C45H82N11O17P3
• M. W.: 1142.117363
• Purity: ≥95%

SYNONYMS

• IUPAC name: tetrakis(cyclohexanamine); {[(2R,3R,4R,5R)-2-(6-amino-9H-purin-9-yl)-5-[({[({[(2R,3S,4R,5R)-5-(3-carbamoyl-1,4-dihydropyridin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)methyl]-4-hydroxyoxolan-3-yl]oxy}phosphonic acid
• IUPAC Traditional name: tetrakis(cyclohexylamine); nadph
• Synonyms: β-NADPH; NADPH; TPNH; Triphosphopyridine nucleotide, reduced form

DATABASE IDS

• CAS Number: 100929-71-3
• MDL Number: MFCD00079504

PROPERTIES

• Cation Traces: Na: ≤0.1%
• Empirical Formula (Hill Notation): C21H30N7O17P3 · 4C6H13N
• Purity: ≥95%
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• Storage Temperature: -20°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Electron donor; cofactor for nitric oxide synthetase
Preparation Note
Chemically reduced.
Application
β-Nicotinamide adenine dinucleotide 2′-phosphate (NADP+) and β-Nicotinamide adenine dinucleotide 2′-phosphate, reduced (NADPH) comprise a coenzyme redox pair (NADP+:NADPH) involved in a wide range of enzyme catalyzed oxidation reduction reactions. The NADP+/NADPH redox pair facilitates electron transfer in anabolic reactions such as lipid and cholesterol biosynthesis and fatty acyl chain elongation. The NADP+/NADPH redox pair is used in a variety of antioxidation mechanism where it protects agains reactive oxidation species accumulation. NADPH is generated in vivio by the pentose phosphate pathway (PPP).

Description (简体中文)

Biochem/physiol Actions
Electron donor; cofactor for nitric oxide synthetase
Preparation Note
Chemically reduced.
Application
β-Nicotinamide adenine dinucleotide 2′-phosphate (NADP+) and β-Nicotinamide adenine dinucleotide 2′-phosphate, reduced (NADPH) comprise a coenzyme redox pair (NADP+:NADPH) involved in a wide range of enzyme catalyzed oxidation reduction reactions. The NADP+/NADPH redox pair facilitates electron transfer in anabolic reactions such as lipid and cholesterol biosynthesis and fatty acyl chain elongation. The NADP+/NADPH redox pair is used in a variety of antioxidation mechanism where it protects agains reactive oxidation species accumulation. NADPH is generated in vivio by the pentose phosphate pathway (PPP).