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Bromoacetic acid N-hydroxysuccinimide ester_Molecular_structure_CAS_42014-51-7)
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Bromoacetic acid N-hydroxysuccinimide ester

Catalog No. B8271 Name Sigma Aldrich
CAS Number 42014-51-7 Website http://www.sigmaaldrich.com
M. F. C6H6BrNO4 Telephone 1-800-521-8956
M. W. 236.02014 Fax
Purity ~95% Email
Storage Chembase ID: 155192

SYNONYMS

IUPAC name
2,5-dioxopyrrolidin-1-yl 2-bromoacetate
IUPAC Traditional name
2,5-dioxopyrrolidin-1-yl 2-bromoacetate

DATABASE IDS

MDL Number MFCD00058571
CAS Number 42014-51-7
PubChem SID 24892067

PROPERTIES

Empirical Formula (Hill Notation) C6H6BrNO4
Purity ~95%
Quality Level PREMIUM
Shipped in dry ice
Apperance powder
Solubility acetone: soluble25 mg/mL
Solubility DMF: soluble
GHS Pictograms GHS07
GHS Signal Word Warning
GHS Hazard statements H315-H319-H335
European Hazard Symbols Irritant Irritant (Xi)
MSDS Link Download
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
GHS Precautionary statements P261-P305 + P351 + P338
Risk Statements 36/37/38
Safety Statements 26-36
Storage Temperature -20°C
German water hazard class 3

DETAILS

Description (English)
Application
A heterobifunctional cross-linking reagent which allows bromoacetylation of primary amine groups followed by coupling to sulfhydryl-containing compounds. Typically, initial reaction couples via ester to primary amine by amide bond formation in the pH range 6.5-8.5. The second reaction results in thioether bonding in pH range 7.0-8.0.
Caution
The bromoacetyl group is light sensitive.
Description (简体中文)
Application
A heterobifunctional cross-linking reagent which allows bromoacetylation of primary amine groups followed by coupling to sulfhydryl-containing compounds. Typically, initial reaction couples via ester to primary amine by amide bond formation in the pH range 6.5-8.5. The second reaction results in thioether bonding in pH range 7.0-8.0.
Caution
The bromoacetyl group is light sensitive.

REFERENCES