Bromoacetic acid N-hydroxysuccinimide ester

• Catalog No.: B8271
• CAS Number: 42014-51-7
• M. F.: C6H6BrNO4
• M. W.: 236.02014
• Purity: ~95%

SYNONYMS

• IUPAC name: 2,5-dioxopyrrolidin-1-yl 2-bromoacetate
• IUPAC Traditional name: 2,5-dioxopyrrolidin-1-yl 2-bromoacetate

DATABASE IDS

• MDL Number: MFCD00058571
• CAS Number: 42014-51-7
• PubChem SID: 24892067

PROPERTIES

• Empirical Formula (Hill Notation): C6H6BrNO4
• Purity: ~95%
• Quality Level: PREMIUM
• Shipped in: dry ice
• Apperance: powder
• Solubility: acetone: soluble25 mg/mL
• Solubility: DMF: soluble
• GHS Signal Word: Warning
• GHS Hazard statements: H315-H319-H335
• European Hazard Symbols: Irritant (Xi)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• GHS Precautionary statements: P261-P305 + P351 + P338
• Risk Statements: 36/37/38
• Safety Statements: 26-36
• Storage Temperature: -20°C
• German water hazard class: 3

DETAILS

Description (English)

Application
A heterobifunctional cross-linking reagent which allows bromoacetylation of primary amine groups followed by coupling to sulfhydryl-containing compounds. Typically, initial reaction couples via ester to primary amine by amide bond formation in the pH range 6.5-8.5. The second reaction results in thioether bonding in pH range 7.0-8.0.
Caution
The bromoacetyl group is light sensitive.

Description (简体中文)

Application
A heterobifunctional cross-linking reagent which allows bromoacetylation of primary amine groups followed by coupling to sulfhydryl-containing compounds. Typically, initial reaction couples via ester to primary amine by amide bond formation in the pH range 6.5-8.5. The second reaction results in thioether bonding in pH range 7.0-8.0.
Caution
The bromoacetyl group is light sensitive.