Cefaclor

• Catalog No.: C6895
• CAS Number: 53994-73-3
• M. F.: C15H14ClN3O4S
• M. W.: 367.80736

SYNONYMS

• IUPAC name: (6R,7R)-7-[(2R)-2-amino-2-phenylacetamido]-3-chloro-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• IUPAC Traditional name: cefaclor

DATABASE IDS

• Beilstein Number: 8176092
• EC Number: 258-909-5
• MDL Number: MFCD00151471
• CAS Number: 53994-73-3
• PubChem SID: 24278331

PROPERTIES

• Empirical Formula (Hill Notation): C15H14ClN3O4S
• GHS Signal Word: Danger
• GHS Hazard statements: H317-H334
• European Hazard Symbols: Harmful (Xn)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Faceshields, Gloves
• GHS Precautionary statements: P261-P280-P342 + P311
• Risk Statements: 42/43
• RTECS: XI0363000
• Safety Statements: 22-36/37-45
• German water hazard class: 2

DETAILS

Description (English)

Application
Cefaclor is used to study the mechanism of human renal transporters such as hOAT1, hPEPT1, and hPEPT2. Used to study the effects of inhibition of penicillin-binding proteins on bacterial cell wall mucopeptide synthesis.
Cefaclor is used to study urinary tract, intra-abdominal, and Haemophilus influenzae infections 1. It is used to study the mechanism of human renal organic anion and peptide transporters such as hOAT1, hPEPT1, and hPEPT2 and to study the effects of inhibition of penicillin-binding proteins on bacterial cell wall mucopeptide synthesis .
Biochem/physiol Actions
Cefaclor is active against Gram-negative and Gram-positive bacteria. Excretion of cefaclor is primarily renal. Cefaclor binds to penicillin-binding proteins thereby inhibiting cell wall synthesis 1.

Description (简体中文)

Application
Cefaclor is used to study the mechanism of human renal transporters such as hOAT1, hPEPT1, and hPEPT2. Used to study the effects of inhibition of penicillin-binding proteins on bacterial cell wall mucopeptide synthesis.
Cefaclor is used to study urinary tract, intra-abdominal, and Haemophilus influenzae infections 1. It is used to study the mechanism of human renal organic anion and peptide transporters such as hOAT1, hPEPT1, and hPEPT2 and to study the effects of inhibition of penicillin-binding proteins on bacterial cell wall mucopeptide synthesis .
Biochem/physiol Actions
Cefaclor is active against Gram-negative and Gram-positive bacteria. Excretion of cefaclor is primarily renal. Cefaclor binds to penicillin-binding proteins thereby inhibiting cell wall synthesis 1.