(+)-cis-Diltiazem hydrochloride

• Catalog No.: D2521
• CAS Number: 33286-22-5
• M. F.: C22H27ClN2O4S
• M. W.: 450.97878
• Purity: ≥99% (HPLC)

SYNONYMS

• IUPAC name: (2S,3S)-5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl acetate hydrochloride
• IUPAC Traditional name: diltiazem hydrochloride
• Synonyms: (2S,3S)-(+)-cis-3-Acetoxy-5-(2-dimethylaminoethyl)-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one hydrochloride; CRD-401

DATABASE IDS

• Beilstein Number: 4228706
• MDL Number: MFCD00069252
• CAS Number: 33286-22-5
• EC Number: 251-443-3
• PubChem SID: 24277849

PROPERTIES

• Empirical Formula (Hill Notation): C22H26N2O4S · HCl
• Purity: ≥99% (HPLC)
• GHS Signal Word: Warning
• GHS Hazard statements: H302
• European Hazard Symbols: Harmful (Xn)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• Risk Statements: 22
• RTECS: DL0310000
• Safety Statements: 36
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Blocks slow, or L-type Ca2+ channels; regulates Ca2+ release from intracellular stores in neutrophils; stimulates 1,4-dihydropyridine binding to Ca2+ channels; coronary vasodilator.

Description (简体中文)

Biochem/physiol Actions
Blocks slow, or L-type Ca2+ channels; regulates Ca2+ release from intracellular stores in neutrophils; stimulates 1,4-dihydropyridine binding to Ca2+ channels; coronary vasodilator.