Prostaglandin B2

• Catalog No.: P5390
• CAS Number: 13367-85-6
• M. F.: C20H30O4
• M. W.: 334.4498
• Purity: ≥98%

SYNONYMS

• IUPAC name: 7-{2-[(3S)-3-hydroxyoct-1-en-1-yl]-5-oxocyclopent-1-en-1-yl}hept-5-enoic acid
• IUPAC Traditional name: 7-{2-[(3S)-3-hydroxyoct-1-en-1-yl]-5-oxocyclopent-1-en-1-yl}hept-5-enoic acid
• Synonyms: PGB2; (5Z,13E,15S)-15-Hydroxy-9-oxoprosta-5,8(12),13-trien-1-oic acid

DATABASE IDS

• Beilstein Number: 2153006
• PubChem SID: 24898630
• MDL Number: MFCD00065730
• CAS Number: 13367-85-6

PROPERTIES

• Biological Source: synthetic
• Empirical Formula (Hill Notation): C20H30O4
• Purity: ≥98%
• Apperance: solution
• Flash Point: -9 °C
• Flash Point: 15.8 °F
• Solubility: ethanol: ~100 mg/mL
• Solubility: PBS, pH 7.2: ~2 mg/mL
• Solubility: DMSO: ~50 mg/mL
• GHS Signal Word: Danger
• GHS Hazard statements: H225-H319-H336
• European Hazard Symbols: Flammable (F)
• European Hazard Symbols: Irritant (Xi)
• Personal Protective Equipment: Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
• GHS Precautionary statements: P210-P261-P305 + P351 + P338
• RID/ADR: UN 1231 3/PG 2
• Risk Statements: 11-36-66-67
• Safety Statements: 16-26
• Storage Temperature: -20°C
• Supplemental Hazard Statements: Repeated exposure may cause skin dryness or cracking.
• Hazard Class: 3
• UN Number: 1231
• Packing Group: 2
• German water hazard class: 2

DETAILS

Description (English)

Biochem/physiol Actions
Primary prostaglandin of osteoblasts; induces pulmonary hypertension.
Preparation Note
PGB2 is provided as a solution in methyl acetate. To change the solvent, evaporate the methyl acetate under a gentle stream of nitrogen and immediately add the solvent of choice. PGB2, purged with an inert gas, is soluble in ethanol at ~100 mg/mL, DMSO at ~50 mg/mL and in dimethyl formamide at ~ 75 mg/mL.
Physical form
Prostaglandin B2 is supplied as a solution in methyl acetate

Description (简体中文)

Biochem/physiol Actions
Primary prostaglandin of osteoblasts; induces pulmonary hypertension.
Preparation Note
PGB2 is provided as a solution in methyl acetate. To change the solvent, evaporate the methyl acetate under a gentle stream of nitrogen and immediately add the solvent of choice. PGB2, purged with an inert gas, is soluble in ethanol at ~100 mg/mL, DMSO at ~50 mg/mL and in dimethyl formamide at ~ 75 mg/mL.
Physical form
Prostaglandin B2 is supplied as a solution in methyl acetate