Paromomycin sulfate salt_Molecular_structure_CAS_1263-89-4)

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Paromomycin sulfate salt
Catalog No.	P5057	Name	Sigma Aldrich
CAS Number	1263-89-4	Website	http://www.sigmaaldrich.com
M. F.	C23H47N5O18S	Telephone	1-800-521-8956
M. W.	713.70698	Fax
Purity	≥98%	Email
Storage		Chembase ID: 155167

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SYNONYMS

Title

Paromomycin sulfate salt 硫酸盐

IUPAC name

(2R,3S,4R,5R,6S)-5-amino-6-{[(1R,2R,3S,4R,6S)-4,6-diamino-2-{[(2S,3R,4S,5R)-4-{[(2R,3R,4R,5S,6S)-3-amino-6-(aminomethyl)-4,5-dihydroxyoxan-2-yl]oxy}-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy}-3-hydroxycyclohexyl]oxy}-2-(hydroxymethyl)oxane-3,4-diol; sulfuric acid

IUPAC Traditional name

(2R,3S,4R,5R,6S)-5-amino-6-{[(1R,2R,3S,4R,6S)-4,6-diamino-2-{[(2S,3R,4S,5R)-4-{[(2R,3R,4R,5S,6S)-3-amino-6-(aminomethyl)-4,5-dihydroxyoxan-2-yl]oxy}-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy}-3-hydroxycyclohexyl]oxy}-2-(hydroxymethyl)oxane-3,4-diol; sulfuric acid

DATABASE IDS

EC Number	215-031-7
CAS Number	1263-89-4
PubChem SID	24898585
MDL Number	MFCD00079278
Beilstein Number	5715182

PROPERTIES

Empirical Formula (Hill Notation)	C23H45N5O14 · H2SO4
Potency	≥675 μg per mg
Product Line	BioReagent
Purity	≥98%
Suitability	suitable for cell culture
Apperance	powder
Solubility	H2O: soluble50 mg/mL (store stock solution at 2-8°C. Stable at 37°C for 5 days.)
MSDS Link	Download
RTECS	WK2320000
German water hazard class	2

DETAILS

Description (English)

Application
Recommended for use in cell culture applications at 100 mg/L.
Biochem/physiol Actions
Paromomycin inhibits the initiation and elongation steps of protein synthesis by binding to 16S ribosomal RNA. Paramomycin binds to the A site, which causes defective polypeptide chains to be produced and leads to cell death.
Protocols & Applications
Antibiotic Selector for application, solubility, solution stability, working concentration, and mode of action information

Description (简体中文)