Paromomycin sulfate salt

• Catalog No.: P8692
• CAS Number: 1263-89-4
• M. F.: C23H47N5O18S
• M. W.: 713.70698

SYNONYMS

• Title: Paromomycin sulfate salt 硫酸盐
• IUPAC name: (2R,3S,4R,5R,6S)-5-amino-6-{[(1R,2R,3S,4R,6S)-4,6-diamino-2-{[(2S,3R,4S,5R)-4-{[(2R,3R,4R,5S,6S)-3-amino-6-(aminomethyl)-4,5-dihydroxyoxan-2-yl]oxy}-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy}-3-hydroxycyclohexyl]oxy}-2-(hydroxymethyl)oxane-3,4-diol; sulfuric acid
• IUPAC Traditional name: (2R,3S,4R,5R,6S)-5-amino-6-{[(1R,2R,3S,4R,6S)-4,6-diamino-2-{[(2S,3R,4S,5R)-4-{[(2R,3R,4R,5S,6S)-3-amino-6-(aminomethyl)-4,5-dihydroxyoxan-2-yl]oxy}-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy}-3-hydroxycyclohexyl]oxy}-2-(hydroxymethyl)oxane-3,4-diol; sulfuric acid

DATABASE IDS

• EC Number: 215-031-7
• PubChem SID: 24898967
• CAS Number: 1263-89-4
• MDL Number: MFCD00079278
• Beilstein Number: 5715182

PROPERTIES

• Empirical Formula (Hill Notation): C23H45N5O14 · H2SO4
• Product Line: BioReagent
• Suitability: plant cell culture tested
• RTECS: WK2320000
• German water hazard class: 2

DETAILS

Description (English)

Application
Paromomycin, monomycin, is an aminoglycoside antibiotic used to select genetically transformed plants and plant cells.
Biochem/physiol Actions
Paromomycin inhibits the initiation and elongation steps of protein synthesis by binding to 16S ribosomal RNA. Paramomycin binds to the A site, which causes defective polypeptide chains to be produced and leads to cell death.
Protocols & Applications
Antibiotic Selector for application, solubility, solution stability, working concentration, and mode of action information

Description (简体中文)

Application
Paromomycin, monomycin, is an aminoglycoside antibiotic used to select genetically transformed plants and plant cells.
Biochem/physiol Actions
Paromomycin inhibits the initiation and elongation steps of protein synthesis by binding to 16S ribosomal RNA. Paramomycin binds to the A site, which causes defective polypeptide chains to be produced and leads to cell death.
Protocols & Applications
Antibiotic Selector for application, solubility, solution stability, working concentration, and mode of action information