DL-3-Hydroxynorvaline

• Catalog No.: H4002
• CAS Number: 2280-42-4
• M. F.: C5H11NO3
• M. W.: 133.14574
• Purity: ≥98% (TLC)

SYNONYMS

• IUPAC name: 2-amino-3-hydroxypentanoic acid
• IUPAC Traditional name: 2-amino-3-hydroxypentanoic acid
• Synonyms: 2-Amino-3-hydroxypentanoic acid; α-Amino-β-hydroxyvaleric acid; DL-β-Hydroxynorvaline; HNV; 3-Hydroxy-2-aminopentanoic acid

DATABASE IDS

• CAS Number: 2280-42-4
• Beilstein Number: 1722350
• PubChem SID: 24895609
• MDL Number: MFCD00010516

PROPERTIES

• Empirical Formula (Hill Notation): C5H11NO3
• Purity: ≥98% (TLC)
• GHS Signal Word: Danger
• GHS Hazard statements: H315-H318-H335
• European Hazard Symbols: Irritant (Xi)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• GHS Precautionary statements: P261-P280-P305 + P351 + P338
• Risk Statements: 36/37/38
• Safety Statements: 26
• Storage Temperature: -20°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
3-Hydroxynorvaline (HNV) is a microbial, α amino acid threonine analogue which has antiviral activity (herpes virus) and is toxic to mammalian cells (embryotoxic and teratogenic) presumably via incorporation into proteins. 3-Hydroxynorvaline may be used as an unnatural amino acid to study the fidelity of protein translation at the level of acyl-tRNA editing. 3-Hydroxynorvaline may also be used to study enzymes and molecules involved in threonine metabolism.

Description (简体中文)

Biochem/physiol Actions
Specific threonine antagonist.