Mezerein

• Catalog No.: M5518
• CAS Number: 34807-41-5
• M. F.: C38H38O10
• M. W.: 654.70232
• Purity: ≥97% (HPLC)

SYNONYMS

• IUPAC name: (1R,2R,6S,7S,8R,10S,12R,16S,17R,18R)-6,7-dihydroxy-8-(hydroxymethyl)-4,18-dimethyl-5-oxo-14-phenyl-16-(prop-1-en-2-yl)-9,13,15,19-tetraoxahexacyclo[12.4.1.0^1,^1^1.0^2,^6.0^8,^1^0.0^1^2,^1^6]nonadec-3-en-17-yl 5-phenylpenta-2,4-dienoate
• IUPAC Traditional name: (1R,2R,6S,7S,8R,10S,12R,16S,17R,18R)-6,7-dihydroxy-8-(hydroxymethyl)-4,18-dimethyl-5-oxo-14-phenyl-16-(prop-1-en-2-yl)-9,13,15,19-tetraoxahexacyclo[12.4.1.0^1,^1^1.0^2,^6.0^8,^1^0.0^1^2,^1^6]nonadec-3-en-17-yl 5-phenylpenta-2,4-dienoate
• Synonyms: 12β-[(E,E)-5-Phenyl-2,4-pentadienoyloxy]daphnetoxin

DATABASE IDS

• PubChem SID: 24897019
• CAS Number: 34807-41-5
• Beilstein Number: 1675867
• MDL Number: MFCD00135953

PROPERTIES

• Biological Source: from Daphne mezereum
• Empirical Formula (Hill Notation): C38H38O10
• Purity: ≥97% (HPLC)
• GHS Signal Word: Warning
• GHS Hazard statements: H315-H317
• European Hazard Symbols: Irritant (Xi)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Faceshields, Gloves
• GHS Precautionary statements: P280
• Risk Statements: 38
• RTECS: HB5425500
• Safety Statements: 22-24/25
• Storage Temperature: -20°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Potent second stage tumor promotor and inflammatory agent; activates protein kinase C at nanomolar concentrations.
Other Notes
Phorbol ester analog from the plant Daphne mezereum.

Description (简体中文)

Biochem/physiol Actions
Potent second stage tumor promotor and inflammatory agent; activates protein kinase C at nanomolar concentrations.
Other Notes
Phorbol ester analog from the plant Daphne mezereum.