Prostaglandin F2α tris salt

• Catalog No.: P0424
• CAS Number: 38562-01-5
• M. F.: C24H45NO8
• M. W.: 475.616
• Purity: ≥99%

SYNONYMS

• IUPAC name: 2-amino-2-(hydroxymethyl)propane-1,3-diol; 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3S)-3-hydroxyoct-1-en-1-yl]cyclopentyl]hept-5-enoic acid
• IUPAC Traditional name: 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3S)-3-hydroxyoct-1-en-1-yl]cyclopentyl]hept-5-enoic acid; tris buffer
• Synonyms: PGF2α-Tris; (5Z,9α,11α,13E,15S)-9,11,15-Trihydroxyprosta-5,13-dienoic acid tris salt

DATABASE IDS

• Beilstein Number: 4087514
• PubChem SID: 24898103
• CAS Number: 38562-01-5
• EC Number: 254-002-3
• MDL Number: MFCD00077863

PROPERTIES

• Biological Source: synthetic
• Empirical Formula (Hill Notation): C20H34O5 · C4H11NO3
• Purity: ≥99%
• Apperance: white powder
• Solubility: H2O: soluble1 mg/mL (Aqueous solutions are stable for 30 days at 2-8°C and for several months frozen at -0°C in single use aliquots. Avoid repeated freeze/thaw cycles.)
• Solubility: ethanol: soluble50 mg/mL
• GHS Signal Word: Danger
• GHS Hazard statements: H302-H360
• European Hazard Symbols: Toxic (T)
• Personal Protective Equipment: Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
• GHS Precautionary statements: P201-P308 + P313
• Risk Statements: 60-22
• RTECS: UK8025000
• Safety Statements: 53-45
• Storage Temperature: -20°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Luteolytic prostaglandin that induces parturition. Potent vasoconstrictor of pulmonary, coronary, and cerebral arteriole beds. A positive feedback loop between endometrial PG F2α and luteal oxytocin is responsible for completion of luteolysis.1
Luteolytic prostaglandin that induces parturition. Potent vasoconstrictor of pulmonary, coronary, and cerebral arteriole beds. Also stimulates contraction of smooth muscle, such as in bronchi, with possible involvement in asthma. This effect is at least partially mediated through tachykinin release.

Description (简体中文)

Biochem/physiol Actions
Luteolytic prostaglandin that induces parturition. Potent vasoconstrictor of pulmonary, coronary, and cerebral arteriole beds. A positive feedback loop between endometrial PG F2α and luteal oxytocin is responsible for completion of luteolysis.1
Luteolytic prostaglandin that induces parturition. Potent vasoconstrictor of pulmonary, coronary, and cerebral arteriole beds. Also stimulates contraction of smooth muscle, such as in bronchi, with possible involvement in asthma. This effect is at least partially mediated through tachykinin release.