Kynurenic acid

• Catalog No.: K3375
• CAS Number: 492-27-3
• M. F.: C10H7NO3
• M. W.: 189.16748
• Purity: ≥98%

SYNONYMS

• Title: 犬尿喹啉酸
• IUPAC name: 4-hydroxyquinoline-2-carboxylic acid
• IUPAC Traditional name: kynurenic acid
• Synonyms: 4-羟基喹啉-2-甲酸; 4-Hydroxyquinoline-2-carboxylic acid

DATABASE IDS

• PubChem SID: 24277986
• EC Number: 207-751-5
• CAS Number: 492-27-3
• Beilstein Number: 147451
• MDL Number: MFCD00006753

PROPERTIES

• Empirical Formula (Hill Notation): C10H7NO3
• Purity: ≥98%
• Gene Information: human ... CHRNA1(1134), CHRNA10(57053), CHRNA2(1135), CHRNA3(1136), CHRNA4(1137), CHRNA5(1138), CHRNA6(8973), CHRNA7(1139), CHRNA9(55584), CHRNB1(1140), CHRNB2(1141), CHRNB3(1142), CHRNB4(1143), GRIA3(2892), GRIA4(2893), GRIK1(2897), GRIK2(2898), GRIK3(2899), GRIK4(2900), GRIK5(2901), GUCA2A(2980), GUCA2B(2981), NGFR(4804), SLC23A2(9962)rat ... Gria1(50592), Grik1(29559), Grin2a(24409)
• Melting Point: 275 °C (dec.)(lit.)
• GHS Signal Word: Warning
• GHS Hazard statements: H315-H319-H335
• European Hazard Symbols: Irritant (Xi)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• GHS Precautionary statements: P261-P305 + P351 + P338
• Risk Statements: 36/37/38
• Safety Statements: 26-36
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Kynurenic acid is a non-selective antagonist at NMDA and AMPA/kainate receptors; blocks kainic acid neurotoxicity. Kainic acid also blocks nicotinic acetycholine receptors.

Description (简体中文)

Biochem/physiol Actions
Kynurenic acid is a non-selective antagonist at NMDA and AMPA/kainate receptors; blocks kainic acid neurotoxicity. Kainic acid also blocks nicotinic acetycholine receptors.