Dithranol

• Catalog No.: D2773
• CAS Number: 1143-38-0
• M. F.: C14H10O3
• M. W.: 226.2274
• Purity: ≥90% (HPLC)

SYNONYMS

• Title: 地蒽酚
• IUPAC name: 1,8-dihydroxy-9,10-dihydroanthracen-9-one
• IUPAC Traditional name: anthralin
• Synonyms: Anthralin; 二羟蒽酚; 1,8,9-Anthracenetriol; 1,8-二羟基蒽-9(10H)-酮; 1,8-Dihydroxy-9(10H)-anthracenone; 1,8-Dihydroxyanthrone; 1,8,9-蒽三酚; 蒽林

DATABASE IDS

• MDL Number: MFCD00053409
• Beilstein Number: 2054360
• PubChem SID: 24893712
• CAS Number: 1143-38-0
• EC Number: 214-538-0

PROPERTIES

• Empirical Formula (Hill Notation): C14H10O3
• Purity: ≥90% (HPLC)
• Gene Information: mouse ... Alox12(11684)
• Melting Point: 178-181 °C(lit.)
• GHS Signal Word: Warning
• GHS Hazard statements: H315-H319-H335
• European Hazard Symbols: Irritant (Xi)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• GHS Precautionary statements: P261-P305 + P351 + P338
• Risk Statements: 36/37/38
• RTECS: CB8927000
• Safety Statements: 26
• German water hazard class: 3

DETAILS

Description (English)

Application
Dithranol, an athracene derivative, is a free radical generating mitochondrial poison that induces apoptosis in keratinocytes. Dithranol is being studied as a potential anti-psoriasis medication.

Description (简体中文)

Application
Dithranol, an athracene derivative, is a free radical generating mitochondrial poison that induces apoptosis in keratinocytes. Dithranol is being studied as a potential anti-psoriasis medication.