Sulindac sulfone

• Catalog No.: S1438
• CAS Number: 59864-04-9
• M. F.: C20H17FO4S
• M. W.: 372.4099832
• Purity: ≥97% (TLC)

SYNONYMS

• IUPAC name: 2-{5-fluoro-1-[(4-methanesulfonylphenyl)methylidene]-2-methyl-1H-inden-3-yl}acetic acid
• IUPAC Traditional name: {6-fluoro-3-[(4-methanesulfonylphenyl)methylidene]-2-methylinden-1-yl}acetic acid
• Synonyms: (Z)-5-Fluoro-2-methyl-1-[p-(methylsulfonyl)benzylidene]indene-3-acetic acid

DATABASE IDS

• MDL Number: MFCD01317811
• CAS Number: 59864-04-9
• PubChem SID: 24278693

PROPERTIES

• Empirical Formula (Hill Notation): C20H17FO4S
• Purity: ≥97% (TLC)
• Apperance: , Light Yellow to Dark Yellow (solid or powder)
• Solubility: DMSO: >25 mg/mL
• Solubility: ethanol: soluble3 mg/mL (warm)
• Solubility: acetone: soluble5 mg (plus 0.1 ml)
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Metabolite of sulindac that inhibits cell growth by inducing apoptosis independently of cyclooxygenase inhibition. Inhibits the development and induces regression of premalignant adenomatous polyps.

Description (简体中文)

Biochem/physiol Actions
Metabolite of sulindac that inhibits cell growth by inducing apoptosis independently of cyclooxygenase inhibition. Inhibits the development and induces regression of premalignant adenomatous polyps.