β-Nicotinamide adenine dinucleotide 2′-phosphate reduced tetrasodium salt hydrate

• Catalog No.: N6505
• CAS Number: 2646-71-1(anhydrous)
• M. F.: C21H26N7Na4O17P3
• M. W.: 833.348203
• Purity: ≥95% (HPLC)

SYNONYMS

• Title: 还原型 β-烟酰胺腺嘌呤二核苷酸 2′-磷酸 四钠盐 水合物
• IUPAC name: tetrasodium [(2R,3R,4R,5R)-5-(6-amino-9H-purin-9-yl)-3-hydroxy-4-(phosphonatooxy)oxolan-2-yl]methyl ({[(2S,3R,4S,5S)-5-(3-carbamoyl-1,4-dihydropyridin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphonato}oxy)phosphonate
• IUPAC Traditional name: tetrasodium [(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-3-hydroxy-4-(phosphonatooxy)oxolan-2-yl]methyl {[(2S,3R,4S,5S)-5-(3-carbamoyl-4H-pyridin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphonato}oxyphosphonate
• Synonyms: 二氢烟酰胺腺嘌呤二核苷酸磷酸 四钠盐; 还原型辅酶 II 四钠盐; β-NADPH; 2′-NADPH hydrate; Triphosphopyridine nucleotide reduced tetrasodium salt; 2′-NADPH 水合物; 还原型三磷酸吡啶核苷酸 四钠盐; NADPH Na4; TPNH2 Na4; Coenzyme II reduced tetrasodium salt; Dihydronicotinamide adenine dinucleotide phosphate tetrasodium salt

DATABASE IDS

• CAS Number: 2646-71-1(anhydrous)
• MDL Number: MFCD00036263
• PubChem SID: 24897780

PROPERTIES

• Empirical Formula (Hill Notation): C21H26N7Na4O17P3 · xH2O
• Purity: ≥95% (HPLC)
• Purity: ≥95% (spectrophotometric assay)
• Storage Temperature: -20°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Electron donor; cofactor for many redox enzymes including nitric oxide synthetase
Other Notes
Packaged based on solid weight.
Preparation Note
Enzymatically reduced.
Application
β-Nicotinamide adenine dinucleotide 2′-phosphate (NADP+) and β-Nicotinamide adenine dinucleotide 2′-phosphate, reduced (NADPH) comprise a coenzyme redox pair (NADP+:NADPH) involved in a wide range of enzyme catalyzed oxidation reduction reactions. The NADP+/NADPH redox pair facilitates electron transfer in anabolic reactions such as lipid and cholesterol biosynthesis and fatty acyl chain elongation. The NADP+/NADPH redox pair is used in a variety of antioxidation mechanism where it protects agains reactive oxidation species accumulation. NADPH is generated in vivio by the pentose phosphate pathway (PPP).

Description (简体中文)

Biochem/physiol Actions
电子供体；很多氧化还原酶（包括一氧化氮合成酶）的辅因子
Other Notes
根据固体质量包装。
Preparation Note
Enzymatically reduced.
Application
β-Nicotinamide adenine dinucleotide 2′-phosphate (NADP+) and β-Nicotinamide adenine dinucleotide 2′-phosphate, reduced (NADPH) comprise a coenzyme redox pair (NADP+:NADPH) involved in a wide range of enzyme catalyzed oxidation reduction reactions. The NADP+/NADPH redox pair facilitates electron transfer in anabolic reactions such as lipid and cholesterol biosynthesis and fatty acyl chain elongation. The NADP+/NADPH redox pair is used in a variety of antioxidation mechanism where it protects agains reactive oxidation species accumulation. NADPH is generated in vivio by the pentose phosphate pathway (PPP).