3-(2-Pyridyldithio)propionic acid N-hydroxysuccinimide ester

• Catalog No.: P3415
• CAS Number: 68181-17-9
• M. F.: C12H12N2O4S2
• M. W.: 312.36468
• Purity: ≥95%

SYNONYMS

• Title: 3-(2-吡啶基二硫基)丙酸N-羟基琥珀酰亚胺酯
• IUPAC name: 2,5-dioxopyrrolidin-1-yl 3-(pyridin-2-yldisulfanyl)propanoate
• IUPAC Traditional name: 2,5-dioxopyrrolidin-1-yl 3-(pyridin-2-yldisulfanyl)propanoate
• Synonyms: N-Succinimidyl 3-(2-pyridyldithio)propionate; N-琥珀酰亚胺-3-(2-吡啶二硫代)丙酸酯; SPDP

DATABASE IDS

• CAS Number: 68181-17-9
• PubChem SID: 24898409
• EC Number: 269-034-3
• Beilstein Number: 1548137
• MDL Number: MFCD00009636

PROPERTIES

• Empirical Formula (Hill Notation): C12H12N2O4S2
• Purity: ≥95%
• Apperance: powder
• Melting Point: 84-86 °C(lit.)
• Solubility: acetone: soluble50 mg/mL
• Solubility: DMF: soluble
• GHS Signal Word: Warning
• GHS Hazard statements: H315-H319-H335
• European Hazard Symbols: Irritant (Xi)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• GHS Precautionary statements: P261-P305 + P351 + P338
• Risk Statements: 36/37/38
• Safety Statements: 26-36
• Storage Temperature: -20°C
• German water hazard class: 3

DETAILS

Description (English)

Application
A heterobifunctional cross-linking reagent with amine and sulfhydryl reactivity. Typically, coupled initially to molecules containing primary amines by amide bonds buffered at pH 7.5 (6.5-8.5). Second coupling specific for molecules containing free sulfhydryl by thiol-disulfide exchange buffered at pH 8.0 (7.5-8.5). Alternately, this reagent may be used as a protected thiolating reagent following initial coupling and reduction of linker. Useful for preparation of enzyme immunoconjugates and hapten carrier molecule conjugates. Incorporates 4 atom linker.
Packaging
25, 100 mg in poly bottle
5 mg in glass bottle

Description (简体中文)

Application
A heterobifunctional cross-linking reagent with amine and sulfhydryl reactivity. Typically, coupled initially to molecules containing primary amines by amide bonds buffered at pH 7.5 (6.5-8.5). Second coupling specific for molecules containing free sulfhydryl by thiol-disulfide exchange buffered at pH 8.0 (7.5-8.5). Alternately, this reagent may be used as a protected thiolating reagent following initial coupling and reduction of linker. Useful for preparation of enzyme immunoconjugates and hapten carrier molecule conjugates. Incorporates 4 atom linker.
包装
25, 100 mg in poly bottle
5 mg in glass bottle