NGB 2904 hydrochloride

• Catalog No.: SML0066
• CAS Number: 189061-11-8
• M. F.: C28H30Cl3N3O
• M. W.: 530.9163
• Purity: ≥98% (HPLC)

SYNONYMS

• IUPAC name: N-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl}-9H-fluorene-2-carboxamide hydrochloride
• IUPAC Traditional name: N-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl}-9H-fluorene-2-carboxamide hydrochloride
• Synonyms: N-[4-[4-(2,3-Dichlorophenyl)-1-piperazinyl]butyl]-9H-fluorene-2-carboxamide hydrochloride

DATABASE IDS

• MDL Number: MFCD09971107
• CAS Number: 189061-11-8

PROPERTIES

• Empirical Formula (Hill Notation): C28H29Cl2N3O·HCl
• Purity: ≥98% (HPLC)
• Apperance: white to tan powder
• Solubility: DMSO: ≥25 mg/mL
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
NGB 2904 is a potent and selective dopamine D3 receptor antagonist with a D3/D2 ratio of 800 for rat and high binding affinity (1.4 nM) at the hD3 receptor with 150-fold selectivity for primate D3 receptors over primate D2L receptors. It attenuates the rewarding effects of cocaine and methamphetamine.

Description (简体中文)

Biochem/physiol Actions
NGB 2904 is a potent and selective dopamine D3 receptor antagonist with a D3/D2 ratio of 800 for rat and high binding affinity (1.4 nM) at the hD3 receptor with 150-fold selectivity for primate D3 receptors over primate D2L receptors. It attenuates the rewarding effects of cocaine and methamphetamine.