Fluvastatin sodium hydrate

• Catalog No.: SML0038
• M. F.: C24H27FNNaO5
• M. W.: 451.4630532
• Purity: ≥98% (HPLC)

SYNONYMS

• IUPAC name: sodium (3R,5S)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoate hydrate
• IUPAC Traditional name: sodium (3R,5S)-7-[3-(4-fluorophenyl)-1-isopropylindol-2-yl]-3,5-dihydroxyhept-6-enoate hydrate
• Synonyms: (±)-(3R*,5S*,6E)-7-[3-(4-Fluorophenyl)-1-(1-methyethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic acid sodium salt hydrate

DATABASE IDS

• MDL Number: MFCD20488050

PROPERTIES

• Empirical Formula (Hill Notation): C24H25FNO4 ·Na · xH2O
• Purity: ≥98% (HPLC)
• Apperance: white to tan powder
• Solubility: H2O: ≥9 mg/mL
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Fluvastatin is a competitive inhibitor of hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase, the enzyme that catalyzes the conversion of HMG-CoA to mevalonic acid, the rate-limiting step in cholesterol biosynthesis. Fluvastatin is antilipemic and is used to reduce plasma cholesterol levels and prevent cardiovascular disease.

Description (简体中文)

Biochem/physiol Actions
Fluvastatin is a competitive inhibitor of hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase, the enzyme that catalyzes the conversion of HMG-CoA to mevalonic acid, the rate-limiting step in cholesterol biosynthesis. Fluvastatin is antilipemic and is used to reduce plasma cholesterol levels and prevent cardiovascular disease.