Lazabemide hydrate

• Catalog No.: SML0042
• CAS Number: 103878-84-8(anhydrous)
• M. F.: C8H12ClN3O2
• M. W.: 217.65278
• Purity: ≥97% (HPLC)
• Storage: desiccated

SYNONYMS

• IUPAC name: N-(2-aminoethyl)-5-chloropyridine-2-carboxamide hydrate
• IUPAC Traditional name: lazabemide hydrate
• Synonyms: N-(2-Aminoethyl)-5-chloro-2-pyridinecarboxamide hydrate; Ro 19-6327 hydrate

DATABASE IDS

• CAS Number: 103878-84-8(anhydrous)
• MDL Number: MFCD20488051

PROPERTIES

• Empirical Formula (Hill Notation): C8H10ClN3O · xH2O
• Purity: ≥97% (HPLC)
• Apperance: white to tan powder
• Solubility: DMSO: ≥22 mg/mL
• GHS Signal Word: Warning
• GHS Hazard statements: H302-H319
• European Hazard Symbols: Harmful (Xn)
• GHS Precautionary statements: P305 + P351 + P338
• Risk Statements: 22-36
• Safety Statements: 26
• Storage Condition: desiccated
• Storage Temperature: room temp
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Lazabemide is a selective and reversible monoamine oxidase B (MAO-B) inhibitor and Anti-Parkinson. Also it inhibits monoamine uptake at high concentrations (IC50 values are 86, 123 and > 500 μM for noradrenalin, serotonin and dopamine uptake respectively).

Description (简体中文)

Biochem/physiol Actions
Lazabemide is a selective and reversible monoamine oxidase B (MAO-B) inhibitor and Anti-Parkinson. Also it inhibits monoamine uptake at high concentrations (IC50 values are 86, 123 and > 500 μM for noradrenalin, serotonin and dopamine uptake respectively).