GW788388 Hydrate

• Catalog No.: SML0116
• M. F.: C25H25N5O3
• M. W.: 443.4977
• Purity: ≥98% (HPLC)

SYNONYMS

• IUPAC name: N-(oxan-4-yl)-4-{4-[3-(pyridin-2-yl)-1H-pyrazol-4-yl]pyridin-2-yl}benzamide hydrate
• IUPAC Traditional name: N-(oxan-4-yl)-4-{4-[3-(pyridin-2-yl)-1H-pyrazol-4-yl]pyridin-2-yl}benzamide hydrate
• Synonyms: 4-{4-[3-(Pyridin-2-yl)-1H-pyrazol-4-yl]-pyridin-2-yl}-N-(tetrahydro-2H-pyran-4-yl)benzamide hydrate

DATABASE IDS

• MDL Number: MFCD20527321

PROPERTIES

• Empirical Formula (Hill Notation): C25H23N5O2 · xH2O
• Purity: ≥98% (HPLC)
• Apperance: white to tan powder
• Solubility: DMSO: ≥8 mg/mL
• GHS Signal Word: Danger
• GHS Hazard statements: H301-H400
• European Hazard Symbols: Toxic (T)
• European Hazard Symbols: Nature polluting (N)
• GHS Precautionary statements: P273-P301 + P310
• Risk Statements: 25-50/53
• Safety Statements: 60-61
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
GW788388 is a potent selective inhibitor of TGF-beta type I receptor [activin receptor-like kinase 5 (ALK5)]. GW788388 is orally available with a half-life of approximately 4 hours.

Description (简体中文)

Biochem/physiol Actions
GW788388 is a potent selective inhibitor of TGF-beta type I receptor [activin receptor-like kinase 5 (ALK5)]. GW788388 is orally available with a half-life of approximately 4 hours.