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Zoniporide hydrochloride hydrate_Molecular_structure_CAS_241800-98-6(freebase))
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Zoniporide hydrochloride hydrate

Catalog No. SML0076 Name Sigma Aldrich
CAS Number 241800-98-6(freebase) Website http://www.sigmaaldrich.com
M. F. C17H19ClN6O2 Telephone 1-800-521-8956
M. W. 374.82476 Fax
Purity ≥98% (HPLC) Email
Storage Chembase ID: 155056

SYNONYMS

IUPAC name
N-carbamimidoyl-5-cyclopropyl-1-(quinolin-4-yl)-1H-pyrazole-4-carboxamide hydrate hydrochloride
IUPAC Traditional name
N-carbamimidoyl-5-cyclopropyl-1-(quinolin-4-yl)pyrazole-4-carboxamide hydrate hydrochloride
Synonyms
N-(Aminoiminomethyl)-5-cyclopropyl-1-(5-quinolinyl)-1H-pyrazole-4-carboxamide hydrochloride hydrate

DATABASE IDS

CAS Number 241800-98-6(freebase)
MDL Number MFCD04113213

PROPERTIES

Empirical Formula (Hill Notation) C17H16N6O · xHCl · yH2O
Purity ≥98% (HPLC)
Apperance white to tan powder
Solubility H2O: soluble2 mg/mL, clear (warmed)
MSDS Link Download
Storage Temperature 2-8°C
German water hazard class 3

DETAILS

Description (English)
Biochem/physiol Actions
Zoniporide is a potent and selective inhibitor of Na+/H+ exchanger isoform 1 (NHE-1). IC50 = 59 nM at NHE-1, vs. 12,000 nM at NHE-2; Zoniporide inhibits NHE-1-dependent Na+ update with IC50 of 14 nM.
Description (简体中文)
Biochem/physiol Actions
Zoniporide is a potent and selective inhibitor of Na+/H+ exchanger isoform 1 (NHE-1). IC50 = 59 nM at NHE-1, vs. 12,000 nM at NHE-2; Zoniporide inhibits NHE-1-dependent Na+ update with IC50 of 14 nM.

REFERENCES