Zacopride hydrochloride hydrate

• Catalog No.: SML0081
• CAS Number: 101303-98-4(anhydrous)
• M. F.: C15H23Cl2N3O3
• M. W.: 364.26742
• Purity: ≥98% (HPLC)

SYNONYMS

• IUPAC name: 4-amino-N-{1-azabicyclo[2.2.2]octan-3-yl}-5-chloro-2-methoxybenzamide hydrate hydrochloride
• IUPAC Traditional name: zacopride hydrate hydrochloride
• Synonyms: 4-Amino-N-1-azabicyclo[2.2.2]oct-3-yl-5-chloro-2-methoxybenzamide hydrochloride hydrate

DATABASE IDS

• MDL Number: MFCD20488057
• CAS Number: 101303-98-4(anhydrous)

PROPERTIES

• Empirical Formula (Hill Notation): C15H20ClN3O2 · HCl · xH2O
• Purity: ≥98% (HPLC)
• Apperance: white to tan powder
• Solubility: H2O: ≥10 mg/mL
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Zacopride is a sub-nanomolar antagonist of the serotonin 5-HT3 receptor that also displays agonist-like activity against 5-HT4 receptors. It is a potent anxiolytic in animal models, and also has strong antiemetic effects, and also increases aldosterone levels via activation of 5-HT4 receptor in the adrenal glands.

Description (简体中文)

Biochem/physiol Actions
Zacopride is a sub-nanomolar antagonist of the serotonin 5-HT3 receptor that also displays agonist-like activity against 5-HT4 receptors. It is a potent anxiolytic in animal models, and also has strong antiemetic effects, and also increases aldosterone levels via activation of 5-HT4 receptor in the adrenal glands.