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CP-101,606

Catalog No. SML0053 Name Sigma Aldrich
CAS Number 134234-12-1 Website http://www.sigmaaldrich.com
M. F. C20H25NO3 Telephone 1-800-521-8956
M. W. 327.4174 Fax
Purity ≥98% (HPLC) Email
Storage Chembase ID: 60162

SYNONYMS

IUPAC name
1-[(1S,2S)-1-hydroxy-1-(4-hydroxyphenyl)propan-2-yl]-4-phenylpiperidin-4-ol
IUPAC Traditional name
traxoprodil
Synonyms
Traxoprodil; (1S,2S)-1-(4-hydroxy-phenyl)-2-(4-hydroxy-4-phenylpiperidino)-1-propanol; CP-101606

DATABASE IDS

MDL Number MFCD00926469
CAS Number 134234-12-1

PROPERTIES

European Hazard Symbols Toxic Toxic (T)
European Hazard Symbols Nature polluting Nature polluting (N)
MSDS Link Download
GHS Precautionary statements P273-P301 + P310-P305 + P351 + P338
Risk Statements 25-36-50
Safety Statements 26-45-61
Storage Temperature 2-8°C
German water hazard class 3
GHS Pictograms GHS06
GHS Pictograms GHS09
GHS Signal Word Danger
GHS Hazard statements H301-H319-H400
Empirical Formula (Hill Notation) C20H25NO3
Purity ≥98% (HPLC)
Apperance white to tan powder
Optical Rotation [α]/D +50 to +60° ( c=1, MeOH)
Solubility DMSO: ≥35 mg/mL

DETAILS

Description (English)
Biochem/physiol Actions
Traxoprodil (CP-101,606) is a potent noncompetitive antagonist of N-methyl-D-aspartate (NMDA) receptors, selective for the NR2B subunit. It has been shown to be neuroprotective in animal models of brain injury and stroke.
Description (简体中文)
Biochem/physiol Actions
Traxoprodil (CP-101,606) is a potent noncompetitive antagonist of N-methyl-D-aspartate (NMDA) receptors, selective for the NR2B subunit. It has been shown to be neuroprotective in animal models of brain injury and stroke.

REFERENCES