EMD386088

• Catalog No.: SML0139
• CAS Number: 1171123-46-8
• M. F.: C14H16Cl2N2
• M. W.: 283.19624
• Purity: ≥98% (HPLC)

SYNONYMS

• IUPAC name: 5-chloro-2-methyl-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole hydrochloride
• IUPAC Traditional name: 5-chloro-2-methyl-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole hydrochloride
• Synonyms: 5-Chloro-2-methyl-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-Indole hydrochloride; EMD-386088

DATABASE IDS

• CAS Number: 1171123-46-8
• MDL Number: MFCD09038557

PROPERTIES

• Empirical Formula (Hill Notation): C14H15ClN2 · HCl
• Purity: ≥98% (HPLC)
• Apperance: yellow powder
• Solubility: DMSO: ≥16 mg/mL
• Storage Temperature: 2-8°C

DETAILS

Description (English)

Biochem/physiol Actions
EMD-386088 is a potent serotonin 5-HT6-specific agonist. The IC50 for competition of LSD from 5-HT6 expressed in HEK cells is 7.4 nM, and the EC50 for stimulating cAMP production is 1 nM. EMD-386088 is inactive against other HT receptors except 5-HT3 (IC50 = 34 nM).

Description (简体中文)

Biochem/physiol Actions
EMD-386088 is a potent serotonin 5-HT6-specific agonist. The IC50 for competition of LSD from 5-HT6 expressed in HEK cells is 7.4 nM, and the EC50 for stimulating cAMP production is 1 nM. EMD-386088 is inactive against other HT receptors except 5-HT3 (IC50 = 34 nM).