Acenocoumarol

• Catalog No.: SML0074
• CAS Number: 152-72-7
• M. F.: C19H15NO6
• M. W.: 353.3255
• Purity: ≥98% (HPLC)

SYNONYMS

• IUPAC name: 4-hydroxy-3-[1-(4-nitrophenyl)-3-oxobutyl]-2H-chromen-2-one
• IUPAC Traditional name: acenocumarolo
• Synonyms: (±)-Acenocoumarin; 3-(α-Acetonyl-p-nitrobenzyl)-4-hydroxy-coumarin

DATABASE IDS

• EC Number: 205-807-3
• CAS Number: 152-72-7
• MDL Number: MFCD00137816

PROPERTIES

• Empirical Formula (Hill Notation): C19H15NO6
• Purity: ≥98% (HPLC)
• Apperance: white to tan powder
• Solubility: DMSO, heptane and xylene: ≥17 mg/mL
• GHS Signal Word: Warning
• GHS Hazard statements: H302-H315-H319-H335
• European Hazard Symbols: Harmful (Xn)
• GHS Precautionary statements: P261-P305 + P351 + P338
• Risk Statements: 63-22-36/37/38
• RTECS: GN4900000
• Safety Statements: 26-36/37
• Storage Temperature: -20°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Acenocoumarol is a warfarin analog, an anticoagulant that inhibits Vitamin K epoxide reductase. This results in depletion of the reduced form of vitamin K (vitamin KH2), limiting the gamma-carboxylation and subsequent activation of the vitamin K-dependent coagulation factors II, VII, IX, and X and anticoagulant proteins C and S, resulting in decreased prothrombin levels and the amount of thrombin generated.

Description (简体中文)

Biochem/physiol Actions
Acenocoumarol is a warfarin analog, an anticoagulant that inhibits Vitamin K epoxide reductase. This results in depletion of the reduced form of vitamin K (vitamin KH2), limiting the gamma-carboxylation and subsequent activation of the vitamin K-dependent coagulation factors II, VII, IX, and X and anticoagulant proteins C and S, resulting in decreased prothrombin levels and the amount of thrombin generated.