WZ811

• Catalog No.: SML0088
• CAS Number: 55778-02-4
• M. F.: C18H18N4
• M. W.: 290.36232
• Purity: ≥98% (HPLC)

SYNONYMS

• IUPAC name: N-[(4-{[(pyridin-2-yl)amino]methyl}phenyl)methyl]pyridin-2-amine
• IUPAC Traditional name: N-({4-[(pyridin-2-ylamino)methyl]phenyl}methyl)pyridin-2-amine
• Synonyms: N1,N4-Di-2-pyridinyl-1,4-benzenedimethanamine

DATABASE IDS

• MDL Number: MFCD18086914
• CAS Number: 55778-02-4

PROPERTIES

• Empirical Formula (Hill Notation): C18H18N4
• Purity: ≥98% (HPLC)
• Apperance: white to tan powder
• Solubility: DMSO: ≥7 mg/mL
• GHS Signal Word: Warning
• GHS Hazard statements: H302-H315-H319-H335
• European Hazard Symbols: Harmful (Xn)
• GHS Precautionary statements: P261-P305 + P351 + P338
• Risk Statements: 22-36/37/38
• Safety Statements: 26
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
WZ811 is a potent, specific antagonist of CXCR4 (IC50 = 0.3 nM). WZ811 blocks SDF-1 mediated changes in cellular cAMP levels in U87 glioma cells (IC50 = 1.2 nM) and Matirgel infiltration of MDA-MB-231 cells (IC50 = 5.2 nM).

Description (简体中文)

Biochem/physiol Actions
WZ811 is a potent, specific antagonist of CXCR4 (IC50 = 0.3 nM). WZ811 blocks SDF-1 mediated changes in cellular cAMP levels in U87 glioma cells (IC50 = 1.2 nM) and Matirgel infiltration of MDA-MB-231 cells (IC50 = 5.2 nM).