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IMB-10

Catalog No. SML0022 Name Sigma Aldrich
CAS Number 307525-40-2 Website http://www.sigmaaldrich.com
M. F. C19H15NOS2 Telephone 1-800-521-8956
M. W. 337.4585 Fax
Purity ≥98% (HPLC) Email
Storage Chembase ID: 155035

SYNONYMS

IUPAC name
3-(2-methylphenyl)-5-(3-phenylprop-2-en-1-ylidene)-2-sulfanylidene-1,3-thiazolidin-4-one
IUPAC Traditional name
3-(2-methylphenyl)-5-(3-phenylprop-2-en-1-ylidene)-2-sulfanylidene-1,3-thiazolidin-4-one
Synonyms
3-(2-methylphenyl)-5-(3-phenyl-2-propen-1-ylidene)-2-thioxo-4-thiazolidinone

DATABASE IDS

CAS Number 307525-40-2
MDL Number MFCD20134199

PROPERTIES

Empirical Formula (Hill Notation) C19H15NOS2
Purity ≥98% (HPLC)
Apperance yellow powder
Solubility DMSO: ≥25 mg/mL
GHS Pictograms GHS09
GHS Hazard statements H411
MSDS Link Download
GHS Precautionary statements P273
Safety Statements 61
Storage Temperature 2-8°C
German water hazard class 3

DETAILS

Description (English)
Biochem/physiol Actions
IMB-10 is a ligand for the αMβ2 integrin that stabilizes the binding of the integrin to endogenous ligands such as proMMP-9 and fibrinogen. IMB-10 blocks migration of lymphocyte cell lines and inhibits leukocyte infiltration in a murine thioglycolate-induced peritonitis.
Description (简体中文)
Biochem/physiol Actions
IMB-10 is a ligand for the αMβ2 integrin that stabilizes the binding of the integrin to endogenous ligands such as proMMP-9 and fibrinogen. IMB-10 blocks migration of lymphocyte cell lines and inhibits leukocyte infiltration in a murine thioglycolate-induced peritonitis.

REFERENCES