PL405 trifluoroacetate salt

• Catalog No.: L7670
• M. F.: C73H84F3N15O16
• M. W.: 1484.5341696
• Purity: ≥98% (HPLC)

SYNONYMS

• IUPAC name: (2S)-6-amino-2-(2-{2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-{2-[(2S)-6-amino-2-[(2S)-2-acetamido-3-hydroxypropanamido]hexanamido]acetamido}-3-(pyren-4-yl)propanamido]-3-phenylpropanamido]-3-(1H-indol-3-yl)propanamido]-3-(4-nitrophenyl)propanamido]acetamido}acetamido)hexanamide; trifluoroacetic acid
• IUPAC Traditional name: (2S)-6-amino-2-(2-{2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-{2-[(2S)-6-amino-2-[(2S)-2-acetamido-3-hydroxypropanamido]hexanamido]acetamido}-3-(pyren-4-yl)propanamido]-3-phenylpropanamido]-3-(1H-indol-3-yl)propanamido]-3-(4-nitrophenyl)propanamido]acetamido}acetamido)hexanamide; trifluoroacetic acid
• Synonyms: AcSKGPya-F-W-Nop-GGKNH2 trifluoroacetate salt

DATABASE IDS

• MDL Number: MFCD20036265

PROPERTIES

• Empirical Formula (Hill Notation): C71H83N15O14 · xC2HF3O2
• Purity: ≥98% (HPLC)
• Shipped in: wet ice
• Apperance: white to off-white powder
• Solubility: acetonitrile: water (1:1): ≥10 mg/mL
• GHS Signal Word: Warning
• GHS Hazard statements: H315-H319-H335
• European Hazard Symbols: Irritant (Xi)
• GHS Precautionary statements: P261-P305 + P351 + P338
• Risk Statements: 36/37/38
• Safety Statements: 26
• Storage Temperature: -20°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
PL405 is a specific and high affinity endothelin converting enzyme-2 (ECE-2) fluorigenic substrate. PL405 is cleaved by ECE-2 at the Pya-F amide bond to yield the highly fluorigenic Ac-SKG-Pya.

Description (简体中文)

Biochem/physiol Actions
PL405 is a specific and high affinity endothelin converting enzyme-2 (ECE-2) fluorigenic substrate. PL405 is cleaved by ECE-2 at the Pya-F amide bond to yield the highly fluorigenic Ac-SKG-Pya.