Levocetirizine dihydrochloride

• Catalog No.: L7795
• CAS Number: 130018-87-0
• M. F.: C21H27Cl3N2O3
• M. W.: 461.80968
• Purity: ≥98% (HPLC)

SYNONYMS

• IUPAC name: 2-(2-{4-[(R)-(4-chlorophenyl)(phenyl)methyl]piperazin-1-yl}ethoxy)acetic acid dihydrochloride
• IUPAC Traditional name: (-)-cetirizine dihydrochloride
• Synonyms: (-)-Cetirizine dihydrochloride; 2-[2-[4-[(R)-(4-chlorophenyl)-phenyl-methyl]piperazin-1-yl]ethoxy]acetic acid dihydrochloride; Levocetirizine dihydrochloride

DATABASE IDS

• CAS Number: 130018-87-0
• MDL Number: MFCD07366507

PROPERTIES

• Empirical Formula (Hill Notation): C21H25ClN2O3·2HCl
• Purity: ≥98% (HPLC)
• Apperance: powder
• Solubility: H2O: ≥23 mg/mL
• GHS Signal Word: Warning
• GHS Hazard statements: H302-H400
• European Hazard Symbols: Harmful (Xn)
• European Hazard Symbols: Nature polluting (N)
• GHS Precautionary statements: P273
• Risk Statements: 22-50/53
• Safety Statements: 60-61
• Storage Temperature: room temp
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Levocetirizine hydrochloride is a nonsedating antihistamine. It is a histamine H1-receptor antagonist, the active isomer of cetirizine. Levocetirizine has high bioavailability, high affinity for and occupancy of the H1 receptor.

Description (简体中文)

Biochem/physiol Actions
Levocetirizine hydrochloride is a nonsedating antihistamine. It is a histamine H1-receptor antagonist, the active isomer of cetirizine. Levocetirizine has high bioavailability, high affinity for and occupancy of the H1 receptor.