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Pizotifen

Catalog No. B9688 Name Sigma Aldrich
CAS Number 15574-96-6 Website http://www.sigmaaldrich.com
M. F. C19H21NS Telephone 1-800-521-8956
M. W. 295.44174 Fax
Purity ≥98% (HPLC) Email
Storage Chembase ID: 130384

SYNONYMS

IUPAC name
1-methyl-4-{6-thiatricyclo[8.4.0.03,7]tetradeca-1(14),3(7),4,10,12-pentaen-2-ylidene}piperidine
IUPAC Traditional name
litec
Synonyms
Pizotyline; 4-(9,10-Dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thien-4-ylidene)-1-methylpiperidine
Pizotifen

DATABASE IDS

MDL Number MFCD00864192
CAS Number 15574-96-6
EC Number 239-632-9

PROPERTIES

Apperance powder
Solubility DMSO: ≥8 mg/mL
GHS Pictograms GHS07
GHS Pictograms GHS08
GHS Signal Word Warning
GHS Hazard statements H302-H361
European Hazard Symbols Harmful Harmful (Xn)
MSDS Link Download
GHS Precautionary statements P281
Risk Statements 63-22
RTECS TM7165000
Safety Statements 36/37
Storage Temperature room temp
German water hazard class 3
Empirical Formula (Hill Notation) C19H21NS
Purity ≥98% (HPLC)

DETAILS

Description (English)
Biochem/physiol Actions
Pizotifen is a serotonin antagonist acting mainly at the 5-HT1, 5-HT2A and 5HT2C receptors with some antihistamine activity. It is used for the prevention of vascular headache including migraine and cluster headache.
Description (简体中文)
Biochem/physiol Actions
Pizotifen is a serotonin antagonist acting mainly at the 5-HT1, 5-HT2A and 5HT2C receptors with some antihistamine activity. It is used for the prevention of vascular headache including migraine and cluster headache.

REFERENCES