NU7026

• Catalog No.: N1537
• CAS Number: 154447-35-5
• M. F.: C17H15NO3
• M. W.: 281.3059
• Purity: ≥98% (HPLC)

SYNONYMS

• IUPAC name: 2-(morpholin-4-yl)-4H-benzo[h]chromen-4-one
• IUPAC Traditional name: 2-(morpholin-4-yl)benzo[h]chromen-4-one
• Synonyms: 2-(Morpholin-4-yl)-benzo[h]chromen-4-one

DATABASE IDS

• MDL Number: MFCD06798345
• CAS Number: 154447-35-5

PROPERTIES

• Empirical Formula (Hill Notation): C17H15NO3
• Purity: ≥98% (HPLC)
• Shipped in: wet ice
• Apperance: tan solid
• Solubility: DMSO: soluble3 mg/mL at 60 °C
• Solubility: H2O: insoluble
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (简体中文)

Application
Potent, ATP-competitive. IC50 = 0.23 μM. Selectivity over other PI3K-related kinases (IC50 = 13 μM for PI3K and >100 μM for ATM and ATR).
Biochem/physiol Actions
Cell permeable, small molecule benzochromenone inhibitor of DNA-PK (DNA dependent protein kinase).

Description (English)

Application
Potent, ATP-competitive. IC50 = 0.23 μM. Selectivity over other PI3K-related kinases (IC50 = 13 μM for PI3K and >100 μM for ATM and ATR).
Biochem/physiol Actions
Cell permeable, small molecule benzochromenone inhibitor of DNA-PK (DNA dependent protein kinase).