Jervine

• Catalog No.: J4145
• CAS Number: 469-59-0
• M. F.: C27H39NO3
• M. W.: 425.60346
• Purity: ≥98% (HPLC)

SYNONYMS

• IUPAC name: (1'S,2R,2'R,3R,3aS,5'S,6S,7aR,10'S,11'S)-5'-hydroxy-2',3,6,15'-tetramethyl-3a,4,5,6,7,7a-hexahydro-3H-spiro[furo[3,2-b]pyridine-2,14'-tetracyclo[8.7.0.0^2,^7.0^1^1,^1^6]heptadecane]-7',15'-dien-17'-one
• IUPAC Traditional name: jervine
• Synonyms: (3β, 23β)-17,23-Epoxy-3-hydroxyveratraman-11-one; 11-Ketocyclopamine

DATABASE IDS

• EC Number: 207-417-9
• MDL Number: MFCD01684066
• CAS Number: 469-59-0
• PubChem SID: 24896194

PROPERTIES

• Empirical Formula (Hill Notation): C27H39NO3
• Purity: ≥98% (HPLC)
• Gene Information: human ... EBP(10682)
• Apperance: powder
• Solubility: methanol: >2 mg/mL
• Solubility: H2O: insoluble
• GHS Signal Word: Danger
• GHS Hazard statements: H301
• European Hazard Symbols: Harmful (Xn)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Faceshields, Gloves
• GHS Precautionary statements: P301 + P310
• RID/ADR: UN 2811 6.1/PG 3
• Risk Statements: 22
• RTECS: WG9700000
• Storage Temperature: -20°C
• Hazard Class: 6.1
• UN Number: 2811
• Packing Group: 3
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Jervine is a sonic hedgehog (Shh) pathway inhibitor.

Description (简体中文)

Biochem/physiol Actions
Jervine is a sonic hedgehog (Shh) pathway inhibitor.