Diethylumbelliferyl phosphate

• Catalog No.: D7692
• CAS Number: 897-83-6
• M. F.: C13H15O6P
• M. W.: 298.228361
• Purity: ≥98% (HPLC)

SYNONYMS

• IUPAC name: diethyl 2-oxo-2H-chromen-7-yl phosphate
• IUPAC Traditional name: diethyl 2-oxochromen-7-yl phosphate
• Synonyms: DEUP; UBP

DATABASE IDS

• CAS Number: 897-83-6
• PubChem SID: 24894155

PROPERTIES

• Empirical Formula (Hill Notation): C14H17O6P
• Purity: ≥98% (HPLC)
• Apperance: colorless to yellow oil
• Solubility: DMSO: >5 mg/mL
• GHS Signal Word: Danger
• GHS Hazard statements: H300
• European Hazard Symbols: Toxic (T)
• Personal Protective Equipment: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
• GHS Precautionary statements: P264-P301 + P310
• RID/ADR: UN 2811 6.1/PG 2
• Risk Statements: 25
• RTECS: GN7350000
• Safety Statements: 45
• Storage Temperature: -20°C
• Hazard Class: 6.1
• UN Number: 2811
• Packing Group: 2
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Diethylumbelliferyl phosphate is a selective, potent cholesterol esterase inhibitor. It blocks steroidogenesis primarily by preventing cholesterol transport into the mitochondria of steroidogenic cells. Inhibitors of cholesterol esterase are anticipated to limit the absorption of dietary cholesterol. IC50 = 11.6 μM.

Description (简体中文)

Biochem/physiol Actions
Diethylumbelliferyl phosphate is a selective, potent cholesterol esterase inhibitor. It blocks steroidogenesis primarily by preventing cholesterol transport into the mitochondria of steroidogenic cells. Inhibitors of cholesterol esterase are anticipated to limit the absorption of dietary cholesterol. IC50 = 11.6 μM.